College of Medical and Dental Sciences (MDS), UB

Research Fellow in Bioinformatics

Cancer and Genomic Sciences, College of Medical and Dental Sciences

Birmingham, United Kingdom

Post Title: Research Fellow in Bioinformatics – 81362
Organisation Advertising Description: Cancer and Genomic Sciences, College of Medical and Dental Sciences
Location: Birmingham – UK
Full time/part time: Full time
Duration: Fixed Term Contract for up to 30 months
Grade/band: Grade 7
Salary: Full time starting salary is normally in the range £30,942 to £40,322. With potential progression once in post to £42,792 a year.
Closing Date: 10th November 2019

Play a pivotal role in enabling the research to “Improve outcome for patients with Poor Risk Acute Myeloid Leukaemia” under the supervision of Prof Jean-Baptiste Cazier at the Centre for Computational Biology (CCB). Select, develop and implement optimal integrative mathematical/statistical/computational framework, tools and approaches, such as AI and ML, for the project.

Be specifically responsible for the integrative analysis of multi-modal Acute Myeloid Leukaemia (AML) data generated by the CRUK programme led by Prof Jude Fitzgibbon, Queen Mary University of London, in collaboration with numerous prestigious institutions. This programme sets out to improve on existing treatments for patients with poor risk AML by combining the efforts of 5 established UK groups into a unified programme focusing on new knowledge generation through the integration of Genomic (WGS, RNA-seq) Cell Signalling (Proteomics and Drug testing) and stem cell profiling (CyTOF, normal HSC profiles) in a series of poor risk AML patients.

The CCB is a cross-college initiative combining multiple disciplines across the University and its partners to maximise the analysis and application of Big Data, focusing on Development, Application, and Training. The CCB aims to promote excellence in Computational Biology, Data Science for the Life Sciences, Systems Biology, and Bioinformatics across the range of fundamental and applied sciences, in both the University and allied Healthcare arenas. It federates expertise through world class, independent and collaborative research, as well as teaching to a broad audience, ranging from undergraduates to health care professionals. The CCB provides an environment, both physical and structural, to its ~60 members to foster collaborative work and cross-fertilisation such as the new Compute and Storage for Life Sciences (CaStLeS) infrastructure, a £2.3M initiative in the Birmingham Environment for Academic Research Cloud (BEARCloud).

The work involves;
• Identify, and when necessary develop, the appropriate methods to perform a holistic analysis of the data provided using techniques such as AI and ML.
• Integrative analysis of the multi-modal datasets from pairs to the whole set
• Conducting analysis on the data provided in liaison with the relevant experts
• Contribute to publications and presentations of data resulting from the project

You should have a PhD (or have within 6 months of appointment), or equivalent experience in Bioinformatics, Mathematics, Statistics or Computer Sciences. You’ll need a relevant degree, at a minimum of a 2:1 classification or equivalent. Degree should have links with bioinformatics and data science e.g. biological, biomedical, natural sciences, mathematics and computer science.

Informal enquiries can be sent to CCB Centre Manager, Jessica Mylchreest, j.mylchreest@bham.ac.uk or +44121 414 7012.

Closing date: 10th November 2019

Reference: 81362

To download the full job description and details of this position and submit an electronic application online please click on the Apply Online button below or visit www.hr.bham.ac.uk/jobs. Please quote Job Ref 81362 in all enquiries.

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Quote Reference: Reference: 81362

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