The Doan Laboratory within the Division of Genetic and Genomics at Boston Children’s Hospital is looking for strong post-doctoral applications from highly motivated individuals with an interest in translational genomics of neurodevelopmental disorders. The Doan lab is focused improving the understanding of the underlying genetics of neurodevelopmental disorders (e.g., autism spectrum disorder).
Mental health disorders impact social and cognitive functioning and encompass many phenotypes including autism spectrum disorder (ASD), bipolar disorder and attention deficit hyperactivity disorder (ADHD). Despite being highly heritable conditions that impact an estimated 4.4% of people, the phenotypic heterogeneity is a persistent challenge to gene discovery. Our prior studies suggest that much of the undiscovered genetic risk for these conditions lies in noncoding regions or in somatic cells. We strive to improve the clinical testing for impacted families through a combination of clinical and evolutionary methodologies including rigorous large-scale data generation (DNA, RNA, epigenetic), functional validation, and evolutionary analyses of genomic regions regulating human neural development.
We are seeking an energetic and highly organized post-doctoral fellow with experience in high-throughput sequencing, functional assays, and computational analyses of large datasets. The ideal candidate should be able to work independently or within small groups. The successful candidate will participate in all aspects of the research project, including experimental design, data collection and analysis, preparation of figures, and preparation of manuscripts. Prior achievement as demonstrated by publications/presentations is required and evidence for motivation and independence will be considered. Post-doctoral fellows are expected to apply for or aid in applications for fellowships and grants. Interested candidates should send cover letter, CV, and the names of 3 references to:
• Ph.D. or M.D. Ph.D. in genetics, neurology, or related area
• Experience in DNA sequencing and functional assays
• Computational experience
• Strong writing and public speaking skills
• Excellent organizational and communication skills
• Enjoy working as part of a team
Boston Children’s Hospital and Harvard Medical School are equal opportunity employers and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law.
We particularly encourage applications from women and minority candidates.