Nanyang Technological University (NTU)

Research Fellow

Laboratory of Moledular Immunology & Cell Signaling

Singapore, Singapore

Research Fellow (RF) positions for 3-4 years are available. Starting Annual Salary from SGD 60,000 to 85,000 (Depending on experience) plus health insurance and other benefits. The candidates have to be well trained in molecular cloning, cell biology and Biochemistry, have advanced background knowledge in Immunology or Cancer. The candidates should have genuine interest in basic research. One RF will work on a newly established conditional knockout mouse model to identify functional significance of our target protein in various immune cells. In parallel, the biochemical feature of this novel protein will be characterized. The other RF will work on projects dealing with cancer stem cells in spontaneous mouse cancer model and xenograft mouse model. Candidates are expected to develop the project independently and supervise undergraduate/ graduate students and research assistants. 


Candidate should;

1.   possess a PhD degree in Biological Sciences, Medicine or related disciplines

2.   be able to acquire and analyse flow cytometry data using 5 laser Fortessa

3.   perform molecular cloning, tissue culture, animal experiments and biochemistry analyses using primary cells isolated from mice

4.   able to use open source bioinformatics tools

5.   have excellent analytical, technical and problem solving skills

6.   be highly motivated

7.   have first author publications in international peer-reviewed journals

8.   be committed and able to work flexible hours

9.   have good common sense with excellent communication, writing and presentation skills

 

Nanyang Technological University, School of Biological Sciences, Singapore

Young and research-intensive, Nanyang Technological University (NTU, Singapore) is ranked 12th globally. It is also placed 1st among the world’s best young universities. NTU offers an excellent environment for research and training of scientific skills.


Why Singapore?

Singapore is a vibrant and safe tropical city, with rich Asian heritage and modern style of living. Singapore offers an exceptional professional and personal experience with an established and vibrant research environment, highly skilled and educated workforce, and good industrial infrastructure.


For more information, check our selected publications;

1.        Venkatesan, N., Wong, J. F., Tan, K. P., Chung, H. H., Yau, Y. H., Cukuroglu, E., Allahverdi, A., Nordenskiold, L., Goke, J., Geifman-Shochat, S., Lin, V. C. L., Madhusudhan, M. S., and Su, I. H. (2018) EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms. Oncogene 37, 461-477

2.        Lim, T. J. F., and Su, I. H. (2018) Talin1 Methylation Is Required for Neutrophil Infiltration and Lipopolysaccharide-Induced Lethality. J Immunol 201, 3651-3661

3.        Loh, J. T., Lim, T. J. F., Ikumi, K., Matoba, T., Janela, B., Gunawan, M., Toyama, T., Bunjamin, M., Ng, L. G., Poidinger, M., Morita, A., Ginhoux, F., Yamazaki, S., Lam, K. P., and Su, I. H. (2018) Ezh2 Controls Skin Tolerance through Distinct Mechanisms in Different Subsets of Skin Dendritic Cells. iScience 10, 23-39

4.        Gunawan, M., Venkatesan, N., Loh, J. T., Wong, J. F., Berger, H., Neo, W. H., Li, L. Y. J., La Win, M. K., Yau, Y. H., Guo, T., See, P. C. E., Yamazaki, S., Chin, K. C., Gingras, A. R., Shochat, S. G., Ng, L. G., Sze, S. K., Ginhoux, F., and Su, I. H. (2015) The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin. Nature Immunology 16, 505-516

5.        Su, I., Dobenecker, M. W., Dickinson, E., Oser, M., Basavaraj, A., Marqueron, R., Viale, A., Reinberg, D., Wulfing, C., and Tarakhovsky, A. (2005) Polycomb group protein Ezh2 controls actin polymerization and cell signaling. Cell 121, 425-436

6.        Su, I. H., Basavaraj, A., Krutchinsky, A. N., Hobert, O., Ullrich, A., Chait, B. T., and Tarakhovsky, A. (2003) Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nature Immunology 4, 124-131

 

Please send your CV and reference contacts to Associate Prof. I-hsin Su ihsu@ntu.edu.sg

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Position

Research Fellow