University of Glasgow
College of Medical, Veterinary & Life Sciences
Research Institute of Molecular Cell and Systems Biology
Grade 7: £35,845 – £40,322 per annum
Vacancy Ref: 029334
We have an exciting opportunity for a post-doctoral Research Associate to make a leading contribution to the project: MitoROS: Mitochondrial ROS mapping and control with sub-organellar resolution, working with PI Professor Kostas Tokatlidis at the IMCSB/MVLS and in collaboration with the Co-I Prof Richard Hartley (School of Chemistry).
We are looking for an ambitious, highly motivated, independent and self-driven researcher, to develop this project with a vision to make a significant contribution in the field of mitochondrial biology.
Specifically, the postholder will conduct, manage and publish research in the area of mitochondria biogenesis, function, dynamics and architecture and how they are underpinned by redox regulation. To this end, a multidisciplinary approach will be used combining biochemical, cell and chemical biology and Fluorescence and Super Resolution Imaging approaches. This will include mapping mitochondrial ROS with sub-organellar resolution with dual nanoscale labelling using Halo and SNAP tags, understanding the dynamic changes imparted by redox and metabolic stresses and elucidating the response mechanisms to intramitochondrial morphology changes and antioxidant protein targeting to the organelle. The project is key to advancing our fundamental knowledge in essential aspects of mitochondrial biology but also presents exciting opportunities for translational applications in novel mitochondria targeting approaches in the context of human diseases. The project will benefit from strong international links with leading mitochondrial biology, structural biology and chemical biology labs and requires strong experience in biochemistry/molecular cell biology.
Please visit our website for further information on the Institute and the group :
For more information and to apply online: https://www.gla.ac.uk/explore/jobs/
The post is funded for 3 years in the first instance (BBSRC grant), starting ideally in January 2020 (flexible start).
Informal enquiries can be made to Professor Kostas Tokatlidis (Kostas.email@example.com)
Closing date: 14 November 2019
It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.
We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equity.
The University of Glasgow, charity number SC004401.