Imperial College London (ICL)

Research Associate in Cancer Chemical Biology

Imperial College London (ICL)

London, United Kingdom

Research Associate in Cancer Chemical Biology

Department/Division/Faculty: Chemistry

Salary: £40,215 – £47,579 per annum*

Full-time, fixed term for 12 months in the first instance.

Campus: White City Campus

We are seeking an outstanding molecular cell/chemical biologist to join a collaborative project between the Tate group at Imperial College and Kura Oncology, a leading clinical cancer drug development company. The position is available full time from May 2020 (or as soon as possible thereafter), for 12 months in the first instance with the potential for extension subject to progress.

The Tate group has developed novel chemical proteomic technologies which reveal the post-translational protein modification landscape of cells in unprecedented detail (e.g. Nature Chem 2019, 552), and has extensive expertise in the application of chemical probes to validate drug targets (e.g. Nature Chem 2018, 599; Nature 2019, 693). You will apply cutting edge chemical biology and chemical proteomic approaches together with advanced in vitro and ex vivo models of cancer to better understand the mode of action of drugs in clinical trials, revealing new therapeutic opportunities and biomarkers to help treat the right cohorts of patients. You will work in close collaboration with Kura Oncology, leveraging their unique package of clinical data to inform your research at the state-of-the art £170M Molecular Sciences Research Hub at Imperial’s new White City Campus.

Essential criteria for the role are as follows:

  • A PhD in cell and/or chemical biology, chemical proteomics, or a closely related field; or an equivalent level of professional qualifications and experience
  • A strong research track record, preferably evidenced by publications or patents
  • Independent capability and creativity in hypothesis generation and experimental design
  • Experience with mammalian cell culture
  • Ability to set and attain research objectives as part of a multidisciplinary team

Training can be provided in required techniques, but prior experience in at least one of the following areas is highly desirable:

  • Proteomics or chemical proteomics
  • Molecular cell biology (cloning, gene editing, etc.)
  • Bioinformatic pathway/interactome analysis

The Department of Chemistry proudly holds an Athena SWAN Gold Award and strives to provide a working environment where all our staff feel fully supported to flourish and excel.

Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £34,397 – £37,486 per annum.

To apply please visit: https://www.imperial.ac.uk/jobs/description/NAT00678/research-associate-cancer-chemical-biology

For informal enquiries about the post, please contact Professor Ed Tate: e.tate@imperial.ac.uk

(http://www.imperial.ac.uk/tate-group/).

For technical queries during the application process, please contact recruitment@imperial.ac.uk

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research

Committed to equality and valuing diversity. Imperial College is also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer and is working in partnership with GIRES to promote respect for trans people.

Please apply via recruiter’s website.