Research Associate (Fixed Term)
Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute
The Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/).
We are looking for an experienced post-doctoral research associate to join the research team of Professor Robin Franklin. The Franklin lab studies adult CNS progenitors and the biology of the oligodendrocyte lineage. In this project, we are studying changes in ageing oligodendrocytes and how these changes may impact on their ability to support axonal health. The premise of this project is that age-related changes in oligodendrocytes increase neuronal vulnerability and are therefore a potential non-cell autonomous target for treating neurodegenerative diseases.
The postholder will work primarily on undertaking functional studies on rodent-derived oligodendrocytes based on bioinformatic analysis of gene expression changes occurring in aged adult versus young adult oligodendrocytes using a range of in vitro and in vivo models.
We are looking for a candidate who holds a PhD in the field of CNS glial (oligodendrocyte) biology. Skills and experience we are looking for include:
- Research experience since completion of PhD.
- Strong background in primary CNS cell culture.
- At least one publication with first authorship.
- Previous experience with gene manipulation and expression profiling, confocal imaging and analysis, single cell transcriptomics, basic bioinformatics and tissue culture would be highly advantageous.
We are specifically looking for candidates that have effective communication skills and the ability to work in a team. Proven capacity to design, execute, and interpret your own experiments is essential.
Fixed-term: The funds for this post are available for 3 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.
To apply online for this vacancy and to view further information about the role, please visit:
Closing date: 24 November 2019
The closing date for applications is Sunday 24th November with interviews taking place Tuesday 10th December.
Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager
Please quote reference PS21241 on your application and in any correspondence about this vacancy.
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