Do you want to contribute to top quality medical research?
A Research Assistant position in Spatial Chromatin Biology is immediately available in the Bienko lab for Quantitative Genome Biology at the Science for Life Laboratory (SciLifeLab) in Stockholm.
As a Research Assistant, you will be involved in different projects ongoing in the lab aimed at understanding how the spatial arrangement of chromatin in the nucleus of mammalian cells contributes to regulate gene expression and ultimately shape cell identity.
You will work in a dynamic research environment focused on basic genome biology, molecular methods development and oncogenomics (https://bienkocrosettolabs.org/). You will work alongside senior scientists, postdocs and PhD students from many diverse fields and backgrounds, having the opportunity to learn new concepts in biology, developing your experimental skills, and fostering your creativity.Your mission
We have recently developed a new method based on next-generation sequencing, GPSeq (Girelli et al., Nature Biotechnology 2020 in press), which, for the first time, allows studying how different types of chromatin are spatially distributed in the cell nucleus and how DNA in different parts of the nucleus is differentially prone to mutate.
Your primary task will be supporting other experimentalists in the lab, by culturing cells, preparing samples for GPSeq, preparing GPSeq libraries and sequencing them on our NextSeq500 machine.
You will also be trained in our microscopy technique, iFISH, for high-resolution DNA and RNA fluorescence hybridization (FISH) (Gelali et al., Nature Communications 2019).Your profile
Are you meticulous, attentive to detail, well-organized, flexible, patient and self-critical? Are you problem solving-oriented? Do you like helping others, working in a team and have your job well done? Do you like to have your initiative while solving complex problems? Then you are the right person!
You are not expected to know how to design and conduct complex experiments (although you are expected to know how to use a pipette and prepare a buffer), but you are definitely expected to be willing to learn top-quality laboratory work from people with years of experience, and to be constantly willing to improve your skills and performance as an experimentalist.
If you have previously worked with NGS techniques, that’s great! However, we also welcome applications from people without prior experience in NGS who have previously worked with general molecular biology techniques.
In order to be eligible for this position, you must hold a Master’s degree in Biology, Bioengineering, Biomedicine, Medicine or equivalent.What do we offer?
A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.
Location: Solna, SciLifeLabApplication
An employment application must contain the following documents in English:
- A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
- A complete list of publications
- A summary of current work (no more than one page)
- Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances
- Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline)
Welcome to apply at the latest 30th of June 2020.
The application is to be submitted through the Varbi recruitment system.
Permanent position is initiated by a six months trial period.Want to make a difference? Join us and contribute to better health for all