Salary: Grade 6: £28,660 - £34,189 p.a.
We are seeking a Research Assistant - Bioinformatics (Immunology) to join Professor M Dustins lab at the Kennedy Institute of Rheumatology, University of Oxford. The focus of Professor M Dustins work is on the immunological synapse, integrating its role into the 3D tissue context and translation to treatment of human diseases. You will work on analysing surface proteomics data of human dendritic cells (DCs) maturation and T-cell activation.
You will implement existing and develop new softwares and analyses related to mass-spectrometry-based characterisation of human dendritic cell maturation coupled with transcriptomic analysis of publicly available RNA-seq data. You will manage own research, carefully analyse data and report the results and contribute new ideas to move the project forward. You will implement existing and develop new softwares for analyses of single cell data from automated imaging, flow cytometry and RNA sequencing to identify key differences in T cell response to libraries of proteins presented on supported lipid bilayers based on resting and activated human dendritic cell surface proteomes.
You must hold a Master degree or equivalent in systems/computational biology and have relevant background and knowledge in data analysis and computational/systems biology. You will have programming proficiency using programming/scripting languages such as Python, MATLAB or R, as well as have flexibility and willingness to learn new techniques and methodologies. Excellent English communication and organisational skills and the ability to work independently or as part of a team is essential. Strong interdisciplinary research experiences at the interface systems biology and immunology, as well as experience in mass spectrometry data analysis is desirable.
This is a full-time position fixed-term for 12 months.
Owing to the nature of the research at the Kennedy Institute of Rheumatology, this job will require a satisfactory basic Disclosure and Barring Service check.
You will be required to upload a CV and supporting statement as part of your online application.
The closing date for this position is 12.00 noon on Friday 7 June 2019.