Wren Therapeutics Limited

Research Assistant / Associate, Cell-based Assays

Wren Therapeutics

Cambridge, United Kingdom

Job title: Research Assistant / Associate, Cell-based Assays

Location: Central Cambridge

Salary range: Competitive salary. Eligible for
company-wide discretionary annual bonus plan.

Job summary: Wren Therapeutics Limited is seeking to appoint a talented research associate or assistant to join its rapidly growing scientific team. The appointee will assist in running a busy experimental laboratory and will have specific responsibility, amongst other duties, for Wren’s cell-based assays. The appointee will conduct drug discovery research projects, together with other members of the team, and will contribute to the development and application of new methodologies. The successful candidate will have a desire to play a role in discovering new treatments for debilitating diseases, while working in an innovative and fast-paced small company environment.

Responsibilities:
• Day-to-day running of a cell-based experimental platform. Activities will include maintaining cell cultures (cell lines and stem cell derived tissues); performing regular quality control and set up of equipment; preparing and assisting, or independently performing, cell toxicity assays; performing routine laboratory procedures (preparation of buffers, western blot, quantification of proteins, etc); maintaining accurate and current records of experimental work; using appropriate computer software packages effectively to perform and support the analysis of study data; undertaking general laboratory administration and support as required.
• Write or contribute to publications, including making presentations at conferences or exhibiting work at academic or industry conferences.
• Communicate complex ideas and concepts to those with limited knowledge and understanding as well as to peers.
• Mentor and coach colleagues with less experience

Skills, qualifications and experience needed:
• Undergraduate degree in Biology, Chemistry, or a related discipline, at a leading academic institution.
• Extensive experience in cell biology techniques in the context of drug discovery, toxicity assays and florescence imaging.
• Extensive experience in the analysis of data derived from experimental screening methods.
• Research or industry experience in the fields of protein misfolding diseases and/or neurodegeneration would be beneficial (but is not required).
• Evidence of ability to lead, organise and participate in collaborative research projects.
• Evidence of ability to present research findings to a scholarly audience. Developed bibliography of research publications and presentations is desirable.
• Fluency in English.

Closing date for applications: Applications must be received by 21 July 2019

Application procedure: Please send a cover letter and CV to recruitment@wrentherapeutics.com

About Wren Therapeutics (Wren): Wren (www.wrentherapeutics.com) is a spin-off company from the University of Cambridge (UK) and Lund University (Sweden), focused on drug discovery and development for protein misfolding diseases. Wren is advancing an entirely novel approach to address this class of diseases, based on more than a decade of research from its scientific founders focused on the chemical kinetics of the protein misfolding process. These advances make it possible to map, and selectively modulate, the complex and non-linear chemical kinetic networks associated with misfolding proteins and disease. Wren’s predictive, quantitative platform is built on concepts from the physical sciences and is a fundamental shift from the descriptive, qualitative methods of traditional biology, which have failed to successfully address these complex systems. Wren is using its unique approach to develop a broad pipeline of small molecule and antibody therapeutics, as well as diagnostics, spanning neurology, ophthalmology and metabolic diseases.

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Research Assistant / Associate, Cell-based Assays