University of Connecticut (UConn)

Proteomics and Metabolomics Facility Scientist 2

Proteomics and Metabolomics Facility Scientist 2

Storrs, CT, United States

The University of Connecticut Proteomics and Metabolomics Facility (UConn PMF, https://proteomics.uconn.edu) is hiring a Facilities Scientist 2 to assist the Facility Director with quantitative proteomics and metabolomics analysis using advanced mass spectrometry instrumentation and leading bioinformatics software. The PMF opened in 2017 as the University of Connecticut’s first proteomics-focused and full service core facility, and is housed administratively within the Center for Open Research Resources and Equipment (https://core.uconn.edu). The laboratory exists to provide fully customized analysis to more than 70 faculty across multiple UConn campuses and at other regional academic and industry research institutions. The position will be a full-time appointment and will provide a unique opportunity to work in a rapidly growing and highly productive core facility at a large research university currently ranked in the top 25 of all public universities in the U.S. The diverse research community at UConn participates in both basic science and clinical research that provides opportunities for a wide variety of innovative proteomics and metabolomics analysis.


Founded in 1881, the UConn is a Land Grant and Sea Grant institution and member of the Space Grant Consortium. It is the state’s flagship institution of higher education and includes a main campus in Storrs, CT, four regional campuses throughout the state, and 13 Schools and Colleges, including a Law School in Hartford, and Medical and Dental Schools at the UConn Health campus in Farmington. The University has approximately 10,000 faculty and staff and 32,000 students, including nearly 24,000 undergraduates and over 8,000 graduate and professional students. UConn is a Carnegie Foundation R1 (highest research activity) institution, among the top 25 public universities in the nation.

Through research, teaching, service, and outreach, UConn embraces diversity and cultivates leadership, integrity, and engaged citizenship in its students, faculty, staff, and alumni. UConn promotes the health and well-being of citizens by enhancing the social, economic, cultural, and natural environments of the state and beyond. The University serves as a beacon of academic and research excellence as well as a center for innovation and social service to communities. UConn is a leader in many scholarly, research, and innovation areas. Today, the path forward includes exciting opportunities and notable challenges. Record numbers of undergraduate applications and support for student success have enabled the University to become extraordinarily selective.


MINIMUM QUALIFICATIONS

  1. Master’s degree in chemistry, biochemistry, analytical chemistry, or related field,
  2. At least three years of experience implementing high resolution mass spectrometry for advanced proteomics analysis
  3. Extensive familiarity with operating, maintaining, and troubleshooting Thermo Scientific hybrid Orbitrap mass spectrometers and nanoflow ultra-high performance liquid chromatography instrumentation
  4. Publication history that demonstrates successful application of state of the art mass spectrometry for label-free and/or label-based (e.g. Tandem Mass Tags, iTRAQ, SILAC) quantitative proteomics
  5. Proficiency using common proteomics software platforms for peptide/protein identification and quantification such as MaxQuant/Andromeda, Proteome Discoverer, Byonic, and/or Scaffold Q+S
  6. Clear communication skills and the ability to effectively inform researchers with varied scientific backgrounds about the analytical techniques and informatics methods implemented in the core facility
  7. Desire to work in a highly collaborative environment that emphasizes comprehensive analysis and one-on-one consultations with researchers
  8. Competency in lab management including product and consumable ordering, meticulous record keeping and outstanding organizational skills


PREFERRED QUALIFICATIONS

  1. Previous experience with extensive collaborative projects or experience in a core facility setting
  2. Experience with untargeted metabolomics workflows, including sample preparation and analysis using TOF instrumentation
  3. Operation, maintenance, and troubleshooting experience using Waters Synapt G2Si HDMS mass spectrometers and Acquity UPLC instrumentation
  4. Experience with small molecule identification using Progenesis QI, XCMS, and/or other programs
  5. Mastery of sample preparation techniques for downstream proteomics analysis including in-gel digestions, in-solution digestions, co-immunoprecipitations, and processing of whole cell lysates or tissue homogenates
  6. Experience with PTM enrichment, localization, and manual MS/MS analysis


APPOINTMENT TERMS

This is a full-time, 12-month, non-tenure-track position with an anticipated start date of June 1, 2020. Salary will be commensurate with qualifications and experience.


TO APPLY

Please apply online via https://academicjobsonline.org/ajo/jobs/16141 and submit a cover letter, curriculum vitae, and the names and contact information for three professional references. Evaluation of applicants will begin immediately. For more information regarding the Center for Open Research Resources and Equipment (COR²E) please visit https://core.uconn.edu.


At the University of Connecticut, our commitment to excellence is complemented by our commitment to building a culturally diverse community.

Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check. 


This position will be filled subject to budgetary approval.


All employees are subject to adherence to the State Code of Ethics which may be found at http://www.ct.gov/ethics/site/default.asp.


The University of Connecticut is committed to building and supporting a multicultural and diverse community of students, faculty and staff. The diversity of students, faculty and staff continues to increase, as does the number of honors students, valedictorians and salutatorians who consistently make UConn their top choice. More than 100 research centers and institutes serve the University’s teaching, research, diversity, and outreach missions, leading to UConn’s ranking as one of the nation’s top research universities. UConn’s faculty and staff are the critical link to fostering and expanding our vibrant, multicultural and diverse University community. As an Affirmative Action/Equal Employment Opportunity employer, UConn encourages applications from women, veterans, people with disabilities and members of traditionally underrepresented populations.

Please apply via recruiter’s website.