Wellcome Trust Sanger Institute

Principal/Senior Bioinformatician

Wellcome Sanger Institute

Cambridge, United Kingdom

The Opportunity:
The Teichmann lab is seeking a senior or principal (depending on experience) bioinformatician to work under the supervision of Kerstin Meyer, the Principal Investigator of the Lung Cell Atlas.

About the Principal Bioinformatian Role:
You will lead/ coordinate an exciting research project constructing a transcriptomic map of germ cells and gametes across the lifespan. Your primary activities will be to: i) coordinate the project with project partners and team members;
I. analyse single cell and spatial transcriptomics data to characterise the cell states present in the tissue and their communication at different developmental and adult stages and suggested validation strategies to confirm your findings;
II. support and participate in the development of new computational methods to study cellular communication and gene regulatory networks from single-cell and spatial transcriptomics data

About the Senior Bioinformatician Role:
You will plan a programme of research that is original but fits within the general research (Lung Cell Atlas) area of the team, taking into account the relevant literature, own experience, and advice from the team leader and other appropriate scientists.

About Us:
To perform this research, we make use of state-of-the-art technological advances, such as (but not limited to): single cell transcriptomics and chromatin accessibility sequencing, spatial transcriptomics and whole genome sequencing. We have access to extensive collections of sample repositories through collaboration with local and international groups. We are significant contributors to the Human Cell Atlas and the Human Developmental Cell Atlas projects, an international project to systematically map all cells in the body across the lifespan.

About You:
You will be an excellent communicator with the ability to build collaborative working relationships with internal and external stakeholders at all levels.

Essential Skills
Principal Bioinformatician:

• PhD in relevant quantitative discipline (e.g. Computational Biology, Genetics, Bioinformatics, Physics, Engineering or Mathematics)
• Proven understanding and experience in the fields of genomics, data processing and high-throughput data analysis
• Data handling skills
• Critical and analytic thinking around problems
• Excellent experience programming in high level scripting languages (preferably R or python)
• Record of high quality research publications
• Excellent communication skills to allow efficient interactions with collaborators/team members
• Proficient Experience of writing manuscripts for publication
• Highly developed problem-solving skills
• Ability to anticipate needs and problems while creating solutions
• Demonstrable good time management and project management skills
• Supervisory Experience

Senior Bioinformatician:
• PhD in relevant quantitative discipline (e.g. Computational Biology, Genetics, Bioinformatics, Physics, Engineering or Mathematics)
• Data handling skills
• Familiarity with Next Generation Sequencing
• Experience programming in high level scripting languages (preferably R or python)
• Excellent communication skills to allow efficient interactions with collaborators
• Experience of writing manuscripts for publication
• Ability to work collaboratively with internal and external stakeholders at all levels.
• Good problem-solving skills

Other information
Whilst the developments around COVID-19 continue to evolve, the Wellcome Genome Campus is closed for all but essential functions and facilities.

People remain at the centre of everything that we do and the majority of our staff are now working remotely to ensure continuity of operations, making use of remote communication and collaboration tools.

Interviews will be taking place virtually and the successful candidate should expect to be fully supported through remote on-boarding and working from home until the Campus re-opens to all staff. This approach may vary for individuals located overseas and/or where a visa is required and starting will be based on a number of factors, we will be able to provide specialist advice to those affected candidates.

Please apply with your CV and a cover letter outlining your suitability for the role.
Closing Date: 17th July
Applications will be considered on an ongoing basis.

About Us
The Wellcome Sanger Institute is a world leading genomics research centre. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. Our findings are used to improve health and to understand life on Earth. Find out more at www.sanger.ac.uk or follow us on Twitter, Facebook, LinkedIn, Youtube and on our Blog.

Our benefits:
There’s an attractive benefits package on offer at the Wellcome Genome Campus. We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.
As well as the usual benefits you would expect, we go much further:
• 25 days annual leave (extra 1 day to a maximum of 30 days for every year you work)
• Auto-enrolment into a generous Group Defined Contribution Pension Scheme, with enhanced company contribution (for more information, see our Pensions page)
• Up to 2 days annual paid volunteering leave
• Up to 10 days paid Emergency Carers Leave per year
• Family friendly environment including options for flexible and part-time working, an on-site Workplace Nursery salary Sacrifice Schemes for pre-school children and Summer holiday club
• Life Assurance Cover and a Group Income Protection Scheme (if on a contract of 12 months or more)
• Enhanced maternity leave and parental leave
• Access to substantial number of courses and training events onsite
• Private Healthcare Scheme (after 6 months service)
• Eyecare and Dental payment plans
• Concessions and discounts from our corporate perks site

Being part of the Wellcome Genome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:
• Free bus service to and from Campus, covering various routes around Cambridge, Saffron Walden and surrounding villages
• A car-share initiative
• Free parking
• A number of on-site venues where you can meet, eat and socialise with colleagues
• A thriving Sports and Social Club which provides members with subsidised access to a gym, tennis courts, sports hall, fitness classes and a vibrant social calendar of events
Find out more about our Wellcome Genome Campus.

We have recently been awarded an Athena SWAN Silver Award. We will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please apply via recruiter’s website.