C4X Discovery Holdings Plc

Principal Inflammation Bioscientist

C4X Discovery Holdings Plc

Manchester, United Kingdom; London, United Kingdom

Salary: Highly competitive salary depending on experience, with extensive benefits

Hours: 40hrs per week (part time would be considered). Mon-Fri (core hours 10am-4pm)

Location: Manchester or London Office, (currently working largely from home)

Reporting To: VP Biology

C4X Discovery is currently looking to extend its drug discovery team with an experienced, highly motivated Principal Bioscientist with industry experience in the field of Inflammation research to enhance the capability of the team as its drug discovery portfolio grows under C4XD’s Drug Discovery Engine business model. This is an exciting time to join the company following the recent announcement of an exclusive worldwide licensing agreement with Sanofi, worth up to €414 million, for C4XD’s oral pre-clinical IL-17A inhibitor programme. 

You will work in an office-based environment evaluating new targets to add to our pipeline and work as part of multiple project teams to establish and manage the screening cascades for testing compounds both in vitro and in vivo conducted by our outsourcing partners. 

Projects will be focused on delivering multiple pre-clinical candidates spanning different disease indications making this a diverse, fast moving and challenging opportunity for the right applicants. To succeed in this position, you will also require a high, proven level of self-motivation, flexibility and organisational skills. The role forms a key part of C4XD’s Discovery team located in either London or Manchester. 

As part of this role, you will also have the opportunity to develop strategies to validate novel genetic targets identified though the proprietary Taxonomy3 platform in inflammatory disorders. You will work closely with the genetics and commercial teams to realise the transformative potential of this platform in these areas of unmet medical need.

We are looking for candidates with a Bioscience PhD and significant experience in all stages of drug discovery from Target Identification to Candidate Selection. Significant experience in the field of Inflammation Research is essential for this position ideally with knowledge of inflammatory diseases such as Rheumatoid Arthritis and Inflammatory Bowel Disease.

To be successful in this role, you will be able to provide leadership to large, cross-functional or highly skilled projects and enable projects to succeed through effective goal setting and strategic planning. Application of expert knowledge in your area of specialism to directly influence multiple projects and making independent decisions which propel projects forward and enable goals to be met are a vital part of this role. As is the ability to identify potential solutions to more complex challenges and provide expert advice in order to facilitate project progression but also staff development.

C4X Discovery offers a broad selection of health benefits, share options, a generous pension scheme and an annual, discretionary bonus scheme. Part time or flexible working would be considered for this role.

Send CV & cover letter to jobs@c4xdiscovery.com

For a full job description and person specification, visit www.c4xdiscovery.com where you will also find more information on the C4XD Drug Discovery Engine business model and details on how your personal data will be handled throughout the recruitment process.

Apply with CV and Cover Letter

Must be a .doc, .docx, or .pdf file and no larger than 1MBMust be a .doc, .docx, or .pdf file and no larger than 1MB

Principal Inflammation Bioscientist