Faculty of Medicine "Carl Gustav Carus", TU Dresden

Predoctoral Fellow / PhD student (f/m/x)

Faculty of Medicine "Carl Gustav Carus", TU Dresden

Dresden, Germany

Jobs with chances
Jointly expanding knowledge in order to advance medicine.

The main focus of the Division of Nephrology of the Department of Internal Medicine III (Head: Prof. Dr. med. Ch. Hugo) is the diagnosis and treatment of renal diseases and hypertension. Nephrology is a division with a lot of research possibilities with national and international collaborations and includes a wide variety of basic and patient-based clinical research.

The Experimental Lab of the Division of Nephrology has a vacant position for

Predoctoral Fellow / PhD student (f/m/x)

The position is immediately available. The contract is planned for 36 months, but will start with a period of 12 months.

The successful candidate will be incorporated into ongoing DFG- and industry-sponsored projects on the identification and characterization of endothelial regeneration mechanism of the kidney. Our group focuses on regenerative mechanisms in the kidney with respect to molecular and cellular interactions of resident and extrinsic cell types by generating and using transgenic mice, in vivo gene transfer methods and kidney organoids from human iPS cells. Microvascular injury is a common finding in many acute forms of renal injury such as thrombotic microangiopathy, acute renal failure, scleroderma renal crisis, vasculitis and also most types of glomerulonephritis. To study vascular injury and repair mechanisms an inducible model of selective endothelial injury was established (Nephrol Dial Transplant 2008 Apr;23(4):1144-56).

Based on our previous work (J Am Soc Nephrol. 2016 Jun;27(6):1714-26) the PhD student will be expected to work on the characterization of different transgenic mouse strains to identify the source of renal endothelial regeneration. Within her / his work, IHC, FACS, cell sorting, single cell transcriptome and proteome analysis, as well as cell culture assays will be techniques (all of which are established within the group) being used in this thesis / project at the highest possible level. In addition, the longitudinal intravital microscopy of glomerular (and other renal) cells are planned for this project.

Your Profile:

  • We are looking for highly motivated applicants pursuing a PhD thesis with translational potential in experimental nephrology / regenerative medicine
  • A detailed CV (with publications, if available), cover letter and two references should be provided

We offer:

  • We offer an interesting research field with an excellent basic research scientific campus including the Center for Regenerative Therapies Dresden (CRTD), the Medical Faculty, the BIOTEC and the Max-Planck Institute for Cell Biology and Genetics in close neighbourhood to the historic city of Dresden
  • A Position according to the TV-L conditions (E13; 50%)

Women are encouraged to apply. Disabled persons with equal qualification will be preferred.

We kindly ask you to apply preferably via our online form to make the selection process faster and more effective. Of course, we also consider your written application without any disadvantages. We look forward to receiving your application, until January, 03th 2020 online with Registration number MK30919916. For further Information please contact Susanne Dollfus by telephone 0351-458-4233 or by E-Mail: susanne.dollfus@uniklinikum-dresden.de

Please apply via recruiter’s website.

Quote Reference: MK30919916