Job title: Postdoctoral Training Fellow
Location: The Francis Crick Institute, Midland Road, London
Contract: Fixed-term (4 years), Full-time
Salary: Competitive with benefits, subject to skills and experience
Vacancy ID: 11326
We are seeking a highly experienced, interactive and self-motivated Bioinformatician to work on evolutionary biology in renal cancer and melanoma in the group of Dr Samra Turajlic at the Francis Crick Institute. The project builds on our previous work, establishing the first evolutionary classification of cancer and identifying the origin of metastatic clones. It will involve micro-clone dynamics, understanding clonal selection and the role of the tumour microenvironment. The project leverages established translational studies such as TRACERx enal (http://tracerx.co.uk/studies/renal/), as well as novel approaches to tumour sampling and profiling. The successful applicant will have a proven track record of publications, be fluent in at least one of the following programming languages: C++, Python or R. The candidate will utilise mathematical and statistical methods to deconvolute cancer evolution based in particular upon next generation sequencing data, from tumour bulk, single cell, and cell-free material, and including panel, exome, whole genome and transcriptome sequencing. The successful applicant will be based in a multi-disciplinary team of cancer evolutionary biologists and translational research clinicians concerned with both basic evolutionary principles and application of evolutionary rules in the clinic. The candidate will collaborate with other computational scientists at the Francis Crick Institute and have ample opportunities to develop their skills. The Francis Crick Institute offers an impressive computational infrastructure and additional computational resources are available through the CRUK City of London Centre and eMedLab.
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
- If you are interested in applying for this role, please apply via our website.
- The closing date for applications is 15 March 2020 at 23:30.
- All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom