Job title: Postdoctoral Training Fellow in Immunosurveillance – Hayday Laboratory
Location: The Francis Crick Institute, Midland Road, London
Contract: Fixed-term, 4 years
Salary: Competitive with benefits, subject to skills and experience
Vacancy ID: 12867
Dr Hayday’s laboratory focuses on how defined molecules expressed by epithelial cells regulate the composition and activity of gamma delta T cells at body surfaces in model animals and in humans. His team is responsible for the ‘Lymphoid Stress Surveillance’ hypothesis, whereby tissue-associated T cells recognise and respond rapidly to perturbations of epithelial cells. This under-studied biology is distinguishable from conventional T cell responsiveness by its rapidity and by its capacity to monitor perturbations induced by non-microbial challenges, such as carcinogens or oxidative stress. Although under-explored, this biology appears fundamental, being conserved as far back as jawless (agnathan) vertebrates.
Details of research projects currently being undertaken can be seen at: https://www.crick.ac.uk/research/labs/adrian-hayday
Research techniques used in the laboratory include functional genomics, flow cytometry, immunogenetics, tumour biology, and classical techniques of biochemistry and molecular biology.
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute is world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
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- The closing date for applications is 06 January 2020 at 23:45.
- All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.