The Younger Laboratory (Children’s Research Institute, Children’s Mercy Kansas City) is searching for exceptional PhD-level scientists to design, implement, and execute projects focused on genome regulation in the context of rare pediatric diseases. These highly translational projects will center around the development of experimental models and approaches to facilitate the functional characterization of rare genetic variants that we’ve identified in our patients at Children’s Mercy Hospital. Importantly, these projects will carry the potential to directly improve the lives of children impacted by rare genetic diseases.
Applicants must hold a PhD in molecular biology, genetics, or a related field. Postdoctoral experience is preferred (although not absolutely required) for Staff Scientist positions. Applicants must have experience working with mammalian cell culture and a strong knowledge in molecular biology techniques. Candidates that have hands-on experience working with next-generation sequencing technologies are highly encouraged to apply.
Research in The Younger Lab -
The vast majority of rare diseases in children are thought to result from underlying variations in the sequence of their DNA. However, distinguishing the specific genetic variants that cause disease and deciphering their functional consequences remains a major challenge. The Younger Lab integrates a series of research programs (i.e. Variant Identification, Variant Prioritization, Genetic Modeling, and Functional Profiling) to accelerate the process of translating the clinical detection of genetic variants into meaningful and actionable biological discoveries.
Learn more at: www.youngerlab.org.
About the new Children’s Research Institute –
The Children’s Research Institute is creating an integrated research environment where no boundaries exist between science and medicine. In our quest to find answers to pediatric medicine’s most challenging questions, we are collaborating with physicians, scientists, academic colleagues, philanthropic partners and others within our community, and around the world. Our research programs focus on areas such as genomics, clinical pharmacology, immunotherapy and health outcomes. The research building, home to the CRI, is currently under construction and has been carefully designed so research and clinical care come together. It is a new way of working together, not in the silos of closed labs or division based on specialties, but in cross-functional teams aligned together to benefit children.
To Apply -
Send a cover letter outlining your research interests and your curriculum vitae to:
Children’s Mercy Kansas City