The Lee laboratory, located at Brandeis University, is focused on understanding how gene regulation allows a cell to express the requisite set of proteins needed to undergo correct cell fate decisions, such as proliferation and differentiation.
We previously discovered a new translation initiation pathway that regulates translation of specific mRNAs (Lee et al., Nature 2015; Lee et al., Nature 2016). We are seeking two highly motivated postdoctoral scholars to join our team and make fundamental insights into this new mode of gene regulation. We are looking to hire a structural biologist to study transcript-specific translation in initiation complexes. We are additionally seeking a candidate to investigate how novel functions of translation initiation factors drive the gene programs required for correct organismal development. These projects will provide training in a broad set of techniques, including biochemistry, general RNA and molecular biology methods, bioinformatics, and cell-based experiments.
We are interested in applicants from diverse research experience backgrounds, but are particularly interested in applicants with a Ph.D. in molecular and cell biology or biochemistry. Candidates should be enthusiastic about collaborative and interdisciplinary research, be motivated to develop as an independent scientist, and demonstrate excellent scientific communication skills.
Located 7 miles from Boston, Brandeis offers world-class research in the setting of a liberal-arts university, along with being part of the vibrant research community of the greater Boston area.
Qualified candidates should send a cover letter, CV, and contact information for three references to: Dr. Amy Lee at firstname.lastname@example.org
For more information:
Details about the lab can be found at: http://www.bio.brandeis.edu/leelab/
Please also see our recent publications:
· Lee et al, Nature 2015 “eIF3 targets cell-proliferation messenger RNAs for translational activation or repression” (http://dx.doi.org/10.1038/nature14267)
· Lee et al, Nature 2016 “eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation” (http://dx.doi.org/10.1038/nature18954)