A Post-Doctoral Research Position is available in the Laboratory of Dr. Steven Laviolette at the University of Western Ontario, to examine the role of cannabinoid signaling in neural development using human cerebral organoids (mini-brains) as a model system. Our laboratory uses an integrative combination of neuroscience research techniques, including molecular biology, behavioural pharmacology, in vivo single unit and multi-unit neuronal recordings, fast-scan cyclic voltammetry, microdialaysis, MALDI imaging and cerebral organoid models of neuropsychiatric developmental pathology (see J. Neurosci.28:8025-33; PNAS, 109(8):3101-6; J. Neurosci. 31(31):11172-83; Scientific Reports. 2017 Sep 12;7(1):11420.). This project will examine the role of cannabinoid signaling and the effects of exposure to phytocannabinoid and biosynthetically produced cannabinoid compounds in the context of neural development using cerebral organoid models of abnormal brain development in schizophrenia, addiction, anxiety and depression. A strong background in neuronal cell culture systems and molecular neurobiology will be required for this position. Experience with molecular protein assays and/or immunohistochemistry would also be a strong asset.
The tentative start date for the position is January 2020 or earlier. Applications should include a CV and publication list. Please send applications directly to Dr. Steven Laviolette (email@example.com), Dept. of Anatomy & Cell Biology, University of Western Ontario.