Postdoctoral Researcher in Cancer Systems Biology

Case Comprehensive Cancer Center (Case CCC), CWRU

Cleveland, OH, United States

The Varadan Laboratory for Translational Systems Biology within the Case Comprehensive Cancer Center is seeking a highly motivated postdoctoral researcher to work within a growing NIH-funded cross-disciplinary team focused on:

  • Delineating novel mechanisms underlying the pathogenesis of Barrett’s Esophagus and Esophageal Cancer
  • Decoding genetic mechanisms contributing to aggressive cancer phenotypes across population groups. 

The postdoctoral scholar will be integrated within a nationally-recognized multi-investigator team consisting of clinicians and basic scientists within the CWRU GI Specialized Program of Research Excellence (GI SPORE), Barrett’s Esophagus Translational Research Network (BETRNet), P20 Disparities SPORE, and will be an integral member of the cancer genetics program at the Case Comprehensive Cancer Center. Thus, this unique opportunity will involve engagement with a cross-functional team of computational biologists, clinicians, basic scientists and industry collaborators. 



  • Doctoral degree in biomedical sciences with sub-specialties in any of Genetics, Cell Biology, Cancer Biology, Biochemistry, Molecular Biology, Pharmacology, Biotechnology or in other relevant fields
  • Preference will be given to candidates with cancer biology experience and hands-on expertise in molecular techniques routinely used in cancer research including but not limited to, cell culture, sequencing, generation of genetically modified stable cell lines, DNA/RNA/protein assessments, in vitro/in vivo assays etc.
  • This position is open to recent Ph.D graduates, PhD candidates graduating in 2019 are particularly encouraged to apply. Current postdoctoral fellows will also be considered.
  • Applicants are expected to have excellent oral and written communication skills including first-author publications and/or presentations in international conferences.

The Varadan Laboratory is engaged in the integration of large-scale biological datasets coupled with experimental validation in preclinical model systems to solve the most pressing challenges in translational cancer research. Our modeling efforts have resulted in the discovery and validation of: novel therapeutic interventions in ovarian cancer (Oncogene, 2017); mechanisms of disease progression in esophageal cancer (Gastroenterology, 2019); and immune modulation in breast cancer (Clinical Cancer Research, 2016). Our goal is to accelerate the discovery and translation of treatment strategies in complex diseases, thus impacting both the prevention and management of aggressive diseases such as cancer.


To complete an application, please email a cover letter, CV and names of references to:


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Postdoctoral Researcher in Cancer Systems Biology