The National Center for Tumor Diseases (NCT) was founded by the University Clinic Carl Gustav Carus Dresden, the Medical Faculty of the TU Dresden, the Helmholtz-Zentrum Dresden-Rossendorf and the German Cancer Research Center (DKFZ). With its research sites in Dresden and Heidelberg, the NCT is the leading oncology center in Germany and a top center internationally that is committed to individualized, patient-side cancer medicine. We are a NCT Junior Research Group on “Genetic Predisposition and Prevention of acute leukemia of childhood” that is located in the Department of Pediatrics at the University Clinic Dresden (Leader: Prof. Dr. Julia Hauer). The research focus of our team is oncology/immunology with a special interest in inherited predispositions to pediatric cancer and a particular focus on childhood B-cell acute lymphoblastic leukemias (B-ALL) and its potential link to infection exposure. In our previous work we showed that leukemia development is related to infectious rigger in murine models. These results are highly relevant for the human scenario, since in children, B-ALL development peaks between 2-6 years, which coincides with the first immune system challenges through infection exposures encountered for example in daycare, kindergarten or pre-school.
Starting at May 1st, 2020 we are looking for a highly motivated
Postdoctoral Researcher in biology/life science (f/m/x)
This full-time Position is limited for 24 months.
Building on our previous studies in the framework of the project “PreventALL” funded by the European Research Council the here offered postdoctoral position focuses on elucidating the mechanistic link between infection and B-cell leukemia development in-vitro and in in-vivo. The project is highly multifaceted, with a broad range of techniques being used, including cell based assays of cell lines and primary cell cultures, molecular biological methods (cloning, transfection, transduction, CRISPR-Cas9), protein-based assays, in-vivo murine models, as well as next generation sequencing techniques and the corresponding data analysis. Since we believe that collaborations are the key to successful research, our team is well-connected to other research groups within Germany and internationally.
We are looking for a postdoctoral fellow who is highly motivated, energetic and friendly with a strong interest in science and cancer immunology. The ideal candidate is eager to learn new techniques, while being able to work diligently, independently and structured. Since we are a newly established junior group the applicant must be a team player that is flexible, open-minded and willing to be a part of a newly formed lab.
• PhD thesis or equivalent in biology or a similar life science/bioscience
• Laboratory experience with a background in molecular genetics
• FELASA certificate and experience in murine models
• Good English writing and communication skills
• Interesting work with divers “state of the art“ techniques and translational aspects
• Friendly and open-minded team
• International work environment through multiple european and international collaborations (travelling activities)
• Excellent training opportunities
• A position according to the TV-L conditons (E13; 100 %)
Persons with disabilities are encouraged to apply.
We ask you to apply online or per e-mail (one single, complete pdf document), but will also consider applications submitted by standard mail at no disadvantage. Please use registration number KIK0920047.
We are looking forward to your application until March 31th, 2020. For further Information please contact Dr. Franziska Auer (0351-458-4179 or firstname.lastname@example.org)