AbbVie Deutschland GmbH & Co. KG

Post-Doctoral Research Scientist (m/w/d) - Tau Biology, Neuroscience Discovery

AbbVie Deutschland GmbH & Co. KG

Wiesbaden, Germany

Job Description

The position is located within the Tau Biology Group in the Neuroscience Discovery organization at Ludwigshafen and will support a European Innovative Medicines Initiative (IMI) Project. The accomplished neurobiologist will make substantial contributions to the conception and execution of new therapeutic approaches to neurodegenerative diseases in a collaborative environment. A primary responsibility of the successful candidate will be to develop and execute complex neuronal models of Tau pathology with a focus on Alzheimer Disease. Experience with molecular and cellular biology, neuronal cell culture, microfluidic devices and confocal microscopy would be an asset. The position is offered for 2 years.

Key Objectives:

  • Designing disease-relevant assays and methods to support AbbVie’s contributions and efforts in the IMI project IMPRiND (Inhibiting Misfolded Protein Propagation in Neurodegenerative Disease).
  • Independently design, execute, analyze and interpret experiments to address key scientific questions.
  • Contribute to identify new targets, design and execute target validation studies.
  • Design, establish and validate neuronal models for Alzheimer Disease.
  • Identify, develop and optimize new techniques to address critical project needs.
  • Effectively compile and present scientific plans and data.
  • Read and apply relevant scientific literature to support scientific discussions.
  • Collaborate with other groups in discovery, developmental sciences and global colleagues.


Education and qualification:

  • PhD in neuroscience, cell biology or related fields with at least 2 years of postdoctoral or equivalent industrial experience. Experience in drug discovery would be an advantage.
  • Track-record in neurodegenerative diseases would be desirable.
  • Expertise in protein biochemistry, molecular and cellular biology, including method development and validation.
  • Expertise with culturing primary neurons and/or iPSC-derived neurons and their genetic manipulation.
  • Detailed knowledge on establishing neuronal models in microfluidic devices would be an advantage.
  • Very good skills in planning and coordination of complex interdisciplinary studies.
  • A high degree of self-initiative, independency, flexibility and curiosity.
  • Excellent teamwork and interpersonal relationship skills.
  • Good communication skills and proficiency in English (written and oral).
  • Ability to present scientific activities/results at internal and external meetings, and publish in peer-reviewed journals

We offer you:

  • A fantastic opportunity to work in in a world-class team.
  • A mentor who will assist you as coach and contact person.
  • A supportive environment that allows you to focus on your role and tailor your work to your individual needs, including flexible work models, multiple benefits, and comprehensive health and sports programs.
  • Attractive compensation and company benefits, including our excellent occupational health management system, which is one of the best in Germany.

Additional Information

  • Travel: Yes, 5 % of the Time
  • Job Type: Experienced
  • Schedule: Full-time

Please apply via recruiter’s website.

Quote Reference: 1903372