Postdoctoral Research Scientist
Machine Learning in Cancer
Dr Crispin Miller Laboratory
Starting Salary from £31,604 to £41,929 (Depending on experience) plus relocation allowance where appropriate.
Initial 3 year fixed term contract with possible 2 year extension.
Would you like to develop your scientific career in a research institute that is founded on the quality of its people, acknowledged for its collaborative environment and designed to promote the development of the most outstanding and dedicated scientists? Many early career researchers have already made that decision and at present over 100 of them are now benefiting from our excellent training programme.
The Cancer Research UK Beatson Institute supports cutting edge research into the molecular mechanisms of cancer development and is one of the leading research institutes in Europe. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies, with special emphasis on imaging, metabolomics, and in vivo models.
Our innovative and ambitious research themes focus on understanding the regulation of the tumour microenvironment and cancer metabolism, in particular:
• Intrinsic cancer cell vulnerabilities
• Interplay between the tumour microenvironment, metastasis and recurrence
• Biology of early disease, aimed at developing a ‘Precision Prevention’ approach
The Computational Biology laboratory is focused on the use of Machine Learning approaches to develop a better understanding of the processes that underpin oncogenic transformation. Of major interest to the lab are the regulatory systems that control alternative splicing, transcript stability, and translation in the tumour environment.
A postdoctoral position is available within the group to apply Machine Learning approaches to tumour-derived multi-omics datasets and single cell sequencing data. A particular focus will be on methods that integrate tumour-derived DNA and RNA sequencing data with multi-omics datasets developed from in vitro models within the Institute. These will comprise DNA and RNA sequencing, quantitative proteomics and metabolomics, and will include pulse-chase assays that capture rates of nascent molecule production as well as changes in overall abundance.
While knowledge of genome biology would be advantageous, it is not a pre-requisite: applicants from a numerical background with experience in big data analysis, statistics, and machine learning, are encouraged to apply. The successful applicant will have a relevant PhD, excellent coding skills, a strong grasp of mathematics, and will relish bringing these skills to bear in a highly dynamic and collaborative environment.
For informal enquiries please email Dr Crispin Miller at email@example.com
The Cancer Research UK Beatson Institute is committed to increase the number of female scientists at this level and encourages female applicants to apply. We have recently introduced a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children.
All applications must be made via our website at http://www.beatson.gla.ac.uk/careers/postdoctoral-fellows/.
Closing date for applications: 12 July 2019