The Center for Translational & Computational Neuroimmunology (CTCN), in the Department of Neurology at Columbia University Medical Center (CUMC) is currently seeking a Post-Doctoral Research Scientist in the field of neuroimmunology to join a collaborative project involving proteomics group with Pacific Northwest National Laboratory.
The successful applicant will be immersed into application of proteomics to the research of Alzheimer’s disease and related neuropathologies. An overarching theme of the project will be small sample and single-cell proteomics analysis. It will involve use of capillary and microfluidic sample handling techniques coupled with liquid chromatography and mass spectrometry. The objective of the project will be cataloguing all the different forms and types of microglia that it can take in Alzheimer’s Disease (AD), Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s Disease (PD), and Multiple Sclerosis (MS). The ultimate project outcomes would be development of a microglia atlas and a toolkit for microglia subtyping.
This post-doctoral position provides an opportunity to learn a variety of proteomics techniques and the latest developments in neurodegenerative disease research. More details relevant to this project can be learned from the following publications: