Cancer Research UK (CRUK)

Postdoctoral Research Scientist

Cancer Research UK Beatson Institute

Glasgow, Scotland, United Kingdom

Postdoctoral Research Scientist

Metastasis, recurrence and the cancer microenvironment

Prof Laura M Machesky

Starting Salary from £31,604 to £41,929 (Depending on experience) plus relocation allowance where appropriate. Initial 3 year fixed term contract (with possibility of up to 2 year extension).

Would you like to develop your scientific career in a research institute that is founded on the quality of its people, acknowledged for its collaborative environment and designed to promote the development of the most outstanding and dedicated scientists? Many early career researchers have already made that decision and at present over 100 of them are now benefiting from our excellent training programme.

The Cancer Research UK Beatson Institute supports cutting edge research into the molecular mechanisms of cancer development and is one of the leading research institutes in Europe. The Institute provides an outstanding research environment, underpinned by state-of-the-art core services and advanced technologies, with special emphasis on imaging, metabolomics, and in vivo models.

Our innovative and ambitious research themes focus on understanding the regulation of the tumour microenvironment and cancer metabolism, in particular:

• Intrinsic cancer cell vulnerabilities
• Interplay between the tumour microenvironment, metastasis and recurrence
• Biology of early disease, aimed at developing a ‘Precision Prevention’ approach
The migration, invasion and metastasis group explore the mechanisms behind cancer metastasis and recurrence. We are particularly interested in how actin cytoskeletal dynamics contribute to mechanosensing and how the extracellular matrix and tumour microenvironment affect disseminated cancer cells. We collaborate with physicists and engineers to use a multidisciplinary approach to study cell migration and invasion in a 3D environment. We also use advanced imaging methods such as optogenetics and FRET-FLIM to determine how cells communicate and signal in complex environments. The successful candidate will have the opportunity to be a part of a multidisciplinary team involved in design and use of advanced imaging microscopes for study of the metastatic niche.

Applicants must have a PhD in a relevant field, be ambitious and driven by scientific curiosity. Skills with advanced microscopy, quantitative cell biology, image analysis and molecular biology would be an advantage. A knowledge of or interest in cancer metastasis and the microenvironment is essential. Training will be provided in all areas.

To find out more about this unique opportunity to establish advanced skills and expertise in this exciting field please contact: Professor Laura Machesky

The Cancer Research UK Beatson Institute is committed to increase the number of female scientists at this level and encourages female applicants to apply. We have recently introduced a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children.

All applications must be made via our website at

Closing date for applications is 24 June 2019

Please apply via recruiter’s website.