Max Planck Institute for Biology of Ageing (MPIAGE)

Postdoctoral Research Fellows (m/f/div)

Max Planck Institute for Biology of Ageing (MPIAGE)

Köln, Germany

The Department for “Molecular Genetics of Ageing”
headed by director Prof. Dr. Adam Antebi
is looking for

Postdoctoral Research Fellows (m/f/div)
(job code 02-2021)

The Antebi Department for “Molecular Genetics of Ageing” investigates how regulatory net­works govern animal health and life span. We primarily use the round­worm Caenorhabditis elegans and the tur­quoise killi­fish Notho­branchius furzeri as model organisms, as well as cell culture and mouse. The over­arching goals are to reveal con­served, convergent mechanisms of longevity, and to under­stand how immunity, meta­bolism, and quality control mechanisms cooperate in cellular defense. We apply a multi­disciplinary approach combi­ning genetics, systems biology, cell and mole­cular biology, imaging, biochemistry, and mass spectro­metry in order to understand the biology of ageing and age-related disease. In particular, we have a long-standing interest in under­standing how naturally occurring meta­bolites can serve as signal­ling molecules that regulate animal health and life span, and we are using metabo­lomic approaches to identify such factors.

We seek a highly motivated and talented scientist to join our enthusiastic, colla­borative, and diverse team in an out­standing scientific environment to take part in our exciting research.

Qualifications

The successful applicant will hold a Ph.D. in a relevant research area such as molecular biology, genetics, bio­chemistry, or metabolomics and has a strong track record of accomplish­ment. Prior experience with model organisms (worm, fly, mouse) would be welcome, but is not required. The appli­cant should have a keen interest in the biology of ageing and excellent written and oral communication skills. The working language is English; know­ledge of German is not required.

Research Environment

The Max Planck Institute for Biology of Ageing, Cologne, was founded in 2008 with the aim to under­stand fundamental mechanisms of healthy ageing in various model systems. The institute is part of a net­work of research institutions in the Cologne-Bonn area dedica­ted to research on ageing and age-related disease, consti­tuting a vibrant and collabo­rative environment. Equipped with state-of-the-art tech­nology and excellent core facilities, to which the success­ful candidate will have access, the institute provides out­standing research opportunities for its scientists. At the moment, we host employees from more than 30 diffe­rent nations worldwide.

The employment contract will be based on contracts for the civil service (TVöD Bund, Tarif­vertrag für den öffentlichen Dienst) and will initially be time-limited. The Max Planck Society is committed to employ more dis­abled individuals and especially encourages them to apply. We also seek to increase the number of women in those areas where they are under­represented and particularly encourage them to apply.

Are you interested?

Then please upload your complete application docu­ments, containing a one-page letter with a personal state­ment describing your scientific accomplishments and your interests in our laboratory, your CV and biblio­graphy, as well as contact information for three references, in electronic form as one single PDF file via our online application platform. Applications will be evaluated on a rolling basis until the position is filled.

Informal inquiries are welcome and should be sent to recruitment-AA@age.mpg.de. For further information about the Institute and the Antebi department please see www.age.mpg.de.

Please do consult recent publications from the Antebi department for more information on our scientific projects:

  • Annibal, A., Tharyan, R.G., Schonewolff, M.F., Tam, H., Latza, C., Auler, M.M.K., Gronke, S., Partridge, L., Antebi, A. (2021) Regulation by the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun 12: 3486
  • Tharyan, R.G., Annibal, A., Schiffer, I., Laboy, R., Atanassov, I., Weber, A.L., Gerisch, B., Antebi, A. (2020) NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin. Nat Metab 2: 387-396
  • Kew, C., Huang, W., Fischer, J., Ganesan, R., Robinson, N., Antebi, A. (2020) Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60. Elife 9: e57591
  • Gerisch, B., Tharyan, R.G., Mak, J., Denzel, S.I., Popkes-van Oepen, T., Henn, N., Antebi, A. (2020) HLH-30/TFEB is a Master Regulator of reproductive quiescence. Dev Cell 53: 316-329
  • Tiku, V., Jain, C., Raz, Y., Nakamura, S., Heestand, B., Liu, W., Späth, M., Suchiman, H., Eka, D., Müller, R.U., Slagboom, P.E., Partridge, L., and Antebi, A. (2017) Small nucleoli are a cellular hallmark of longevity. Nat Commun 8: 16083.
 
           

Please apply via recruiter’s website.