The laboratory of Ashlee Rowe at the University of Oklahoma is excited to recruit a motivated and independent postdoctoral research fellow to investigate the biophysical interactions between scorpion venom peptides and pain pathway ion channels for drug discovery. The postdoc will primarily use patch clamp electrophysiology techniques to study the molecular and biophysical interactions between venom peptides and voltage gated sodium ion channel Nav1.8 (and related ion channels Nav1.6, Nav1.7). Specifically, the post doc will characterize the biophysical properties of peptides that inhibit Nav1.8 activity to block pain in a rodent model. The goal of the project is to use venom peptides that inhibit pain pathway ion channels as a platform for drug discovery. The project, supported by an NIH grant to the Oklahoma Center of Biomedical Research Excellence in Structural Biology, provides opportunities to collaborate with molecular biologists and neurophysiologists in the Department of Biology and the Health Science Center, as well as structural and proteomics biologists in the Department of Chemistry and Biochemistry.
This project provides an outstanding opportunity for a motivated postdoctoral researcher to integrate venom peptide pharmacology with sensory neurophysiology to develop novel pain therapeutics. For more information on the Oklahoma Center of Biomedical Research Excellence in Structural Biology, please use the following link.
Up to two years of funding is available with a start date of January 2020 (start date is flexible). Please submit a CV, Letter of Interest with potential start dates, and contact information for three professional references. Additionally, up to three representative publications may be sent as separate pdf files. Candidates from underrepresented STEM groups are encouraged to apply.
Applicants should have a PhD in Biology, Neuroscience, or Physiology by the time of employment. The ideal candidate should have expertise in ion channel electrophysiology, and molecular and cell biology.
Salary Range: $48,000 – $50,000/year
Applicants must submit an ONLINE application at http://jobs.ou.edu for Job Requisition #193165. Computers and personal assistance are available at the Office of Human Resources, 905 Asp, Room 205, Norman, OK 73069. Include job requisition number on all correspondence. Deadlines subject to change with or without notice. For further information on this or other University of Oklahoma job opportunities, please call (405) 325-1826 or access our website at www.hr.ou.edu.
The University of Oklahoma is an Equal Opportunity Employer. Protected veterans and individuals with disabilities are encouraged to apply.