Fred Hutchinson Cancer Research Center

Post-Doctoral Research Fellow, Kemp Laboratory of Functional Precision Medicine

Fred Hutchinson Cancer Research Center

Seattle, WA, United States

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

We are seeking a highly motivated postdoctoral scientist to lead a project in cancer drug target discovery based in the laboratory of Dr. Christopher Kemp. The applicant will apply state of the art functional genomic and high throughput screening approaches to identify genes required for cancer cell survival and sensitizers to current cancer therapeutics. Through bioinformatic curation, functional cellular assays, and animal models, the applicant will prioritize and validate these as candidate drug targets. We currently have identified a number of high value targets that are in stages of validation in patient derived tumor organoids. The ideal candidate will have a formal background in cancer biology and genetics, with expertise in cell culture, including tumor organoids, molecular biology, genetic analysis, and the use of animal models. The applicant will be expected to interact with an interdisciplinary local team (computational scientists, clinicians, cancer biologists) and with the national CTD2 network.

Responsibilities

The applicant will apply state of the art functional genomic and high throughput screening approaches to identify genes required for cancer cell survival and sensitizers to current cancer therapeutics. Through bioinformatic curation, functional cellular assays, and animal models, the applicant will prioritize and validate these as candidate drug targets.

The applicant will be expected to interact with an interdisciplinary local team (computational scientists, clinicians, cancer biologists) and with the national CTD2 network.

Qualifications

  • A PhD in molecular biology, biochemistry, cancer biology, genetics, or related discipline.
  • Experience in standard molecular biology techniques, including qRT-PCR, immunoblotting, shRNA and CRISPR vector design and construction.
  • Experience with drug development would be a plus.
  • Demonstrated track record of productive, independent research.

Please include a cover letter detailing your research accomplishments, go forward interests, and suitability for this position with your application. At least two letters of recommendation will be requested as part of the screening process.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

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Quote Reference: 13963

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