Location: Spring House, Pennsylvania
Requisition ID: 9208190704
Caring for the world, one person at a time has inspired and united the people of Johnson & Johnson for over 130 years. We embrace research and science - bringing innovative ideas, products and services to advance the health and well-being of people. Employees of the Johnson & Johnson Family of Companies work with partners in health care to touch the lives of over a billion people every day, throughout the world.
With $81.6 billion in 2018 sales, Johnson & Johnson is the world’s most comprehensive and broadly-based manufacturer of health care products, as well as a provider of related services, for the consumer, pharmaceutical, and medical devices and diagnostics markets. There are more than 250 Johnson & Johnson operating companies employing approximately 125,000 people in 60 countries throughout the world.
Calling all big thinkers and world-changers who want to drive their careers forward across more than 250 leading businesses in consumer, pharmaceuticals and medical technology. If you have the talent and desire to touch the world, Johnson & Johnson has the career opportunities to help make it happen.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. Janssen Research & Development, LLC discovers and develops creative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.
JanssenBioTherapeuticsis searching for an energetic, highly-motivated Postdoctoral Fellow to carry-out research for next-generation, iPSC-based CAR-T/NK cellplatform for developing novel engineered products for adoptive cell therapy for oncology. Present CAR-T cell immunotherapies show impressive clinical responses, with two CAR-T cell products approved by the FDA for the treatment of B cell malignancies. However, these CAR-T cells are be engineered from patient-specific T cells, which manifest several key shortcomings. This creates an unmet medical need for novel cellular therapies that can overcome these challenges.
Through exploring and leveraging new insights this postdoctoral fellow will conduct research to answer many aspects of iPSC-based CAR-T/NK cell biology that are yet unexplored and define the parameters for building the best-in-class and robust generation of genetically engineered iPSC lines. These iPSC lines will further used by for research activities focused on engineered immune cells and their differentiation into various immunological lineage cells (including T Cells and NK Cells and other immune cells).
Youwill be rewarded with an excellent opportunity to interact with various teams focused on cutting-edge engineered cell therapy platform development. In addition, upon completion of the postdoctoral program, the Fellow will have acquired valuable career experience that enables entry into translational academic settings, biotech-related opportunities, and/or continued development in large pharma.
- Recent Ph.D. in Immunology with a strong background in T cell biology
- A working background in iPSC/CAR-T biology with hands on experience in cell biology, genetic engineering, and assay development is a must.
- Candidate must be able to work permanently in the US.
- Candidatesmustdisplay an ability to independently design and execute research.
- In addition to a broad knowledge of immunology and oncology, we are seeking an individual with deep intellectual curiosity, and excellent communication and interpersonal skills.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
United States-Pennsylvania-Spring House
Janssen Research & Development, LLC. (6084)