As a modern maximum-care hospital with a capacity of approximately 1,540 beds, the University Hospital of Cologne is dedicated to the practice of innovative academic medical excellence. At the Faculty of Medicine 1.800 scientists are engaged in research, ranging from basic sciences to clinical application, as well as teaching and health care. Together with the University Hospital Cologne the faculty maintains 58 clinics, research institutes and centres. 3.400 students study in this dynamic and innovative environment. The Faculty of Medicine and the University Hospital Cologne are embedded in the scientifically highly active Rhine region. They have strong contacts to and alliances with the surrounding universities and non-university research institutions guaranteeing scientific excellence in research and teaching.
As part of our newly established, DFG-funded, collaborative research center (Sonderforschungsbereich) 1399 (Mechanisms of drug sensitivity and resistance in small cell lung cancer) we are hiring a full-time
Postdoctoral Research Fellow (f/m/x)
in the areas of small cell lung cancer in the research group of Prof. Dr. Christian Reinhardt within the Department I for Internal Medicine at the University Hospital Cologne.
The position is limited to 3 years according to WissZeitVG (third-party funded project).
The project will generate a versatile in vivo platform, employing genetically engineered mouse models and in vivo screening tools, to address fundamental questions in SCLC biology and treatment response. We will conduct in vivo PiggyBac-based insertional mutagenesis screens, to search for genes involved in acquired chemotherapy and chemo-immune therapy resistance. In a translational effort and based on rich preliminary data, we will test the hypothesis that SCLCs display enhanced sensitivity against cell cycle checkpoint-abrogating therapeutic interventions.
We are looking for a highly talented scientist driven by the desire to make a relevant contribution to the treatment of cancer patients through exciting scientific discoveries in the lab. Candidates must have obtained a PhD or equivalent to qualify for this post. Prior experience with in vivo cancer models is desirable. Successful candidates will have a strong background in basic molecular and cell biology, immunology, biochemistry or similar areas.
What we have to offer is a vibrant work environment within the highly motivated and strong interacting consortium of the CRC. This offers the opportunity of mentoring and interactions with several global scientific leaders in their respective fields. In addition, the highly collaborative research environment in Cologne provides us with access to state-of-the-art core facilities, including genomics, proteomics and imaging as well as a close connection to the clinics.
Your salary will be based on TV-L.
Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance.
People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.
The position is suitable for staffing with part-time employees.
Please address enquiries to Prof. Dr. Christian Reinhardt: Christian.Reinhardt@uk-koeln.de
Further information is available here:
Have we awakened your interest? Please submit your application (including a detailed CV, list of publications, two references and a brief statement of research interests) via regular mail by 8. December 2019 quoting the reference number V000001437 to
University Hospital Cologne Department of Internal Medicine, Medical Clinic I
Prof. Dr. Christian Reinhardt