The Fine laboratory in the Division of Cardiology at Columbia University Irving Medical Center/New York-Presbyterian Hospital is seeking a highly motivated postdoctoral fellow in basic and translational cardiovascular biology. The lab has cross-disciplinary projects focus on using iPS derived cardiomyocytes and tissue engineering to investigate novel signaling pathways in heart disease. This specific project funding centers on modeling restrictive cardiomyopathy from filamin c mutations in multiple iPS lines with the goal of performing medium throughput drug discovery experiments followed by validation in established mouse models. The lab has a close relationship with both clinical cardiology, genetics and biomedical engineering, using a combination of patient level material (e.g. patient derived iPS cells and serum) and cardiac tissue engineering. The post-doctoral fellow should have an MD, PhD or both and experience with cell culture, standard molecular biology techniques (western blot, RT-PCR, IF, etc.) and genetics. Previous experience with iPS cells, tissue engineering, animal models and genome editing is ideal but not required. Thinking creatively and “outside the box” is especially desired. The fellow will be expected to formulate testable hypotheses, design and execute experiments independently and work well with other members of the research team in a fun and collaborative environment. The long-term goal of the post-doctoral fellowship is to generate several manuscripts and competitively apply for extramural funding towards the goal of an independent research career.
Potential applicants, please send a CV and a brief description of your research interests to Dr. Barry Fine at email@example.com