Postdoctoral Research Fellow
Centre for Inflammation Research
£33,199 – £39,609pa – fixed term until 31st December 2021
The University of Edinburgh, Computational Biologist in integrated multi-omic analysis of metabolomics and single cell RNA sequencing.
We are recruiting a highly motivated post-doctoral researcher who will focus on the application and development of cutting-edge computational methods in the area of integrated multi-Omic analysis of metabolomics and single-cell RNA sequencing. The successful candidate will join Dr Feng’s group in the Centre for Inflammation Research (CIR), and will link closely with Professor Ponting’s group based at the Institute of Genetics and Molecular Medicine (IGMM) and Dr Campbell’s group in the school of chemistry.
The Feng lab has developed a zebrafish model for in vivo live imaging and genetic analysis of pre-neoplastic cells (PNCs) in its initiating niche in vivo. One of the goals of the lab is to dissect mechanisms that regulate how host cells interact with the initial PNCs in its niche, by fully characterising details of lineage development and the cell-cell interaction network using scRNAseq analysis. The single cell RNAseq data will also be integrated with metabolomic data generated through Imaging Mass Spectrometry (IMS) on intact zebrafish PNC niche.
The ideal candidate will have a strong computational background who is keen to develop their skills and knowledge in the rapidly moving field of single cell transcriptomics, keen to explore and establish novel computational methods for integrated multi-Omic analysis. You will apply and develop computational methods for integrated analysis of single cell transcriptome with metabolomics, to allow discovery and interrogation of cellular subpopulations and cellular functional states during tumour initiation.
Excellent communication skills and a genuine enthusiasm for exploring the interface between computational and experimental biology is essential.
This post is available on a fixed term basis, with a working pattern of 35 hours per week until 31st December 2021.
Closing Date: 13th June 2019
For more information and to submit an application, please use the `apply’ button below.