One Research Associate position is available in the Lacroix laboratory at the Western University of Health Sciences (WesternU) in Pomona, California. The Lacroix Laboratory investigates structure-function dynamics and pharmacological mechanisms in mechanosensitive ion channels and develops non-invasive technology to study mechanotransduction in vivo. We use a combination of experimental techniques including protein engineering, patch-clamp electrophysiology, ultrasound stimulation and fluorescence imaging. We are also actively collaborating with other groups on campus and in other institutions. See references [Nat Commun (2018), 9, 2029 and JOVE (2019), 143 doi:10.3791/58781] for examples of recent research from the lab.
The position is available for a highly motivated candidate with a recent PhD in biophysics/biochemistry/pharmacology or any related field. The main task for this position will be to investigate the function of wild-type and mutant ion channels heterologously expressed in mammalian cells using patch-clamp electrophysiology and fluorescence measurements. The candidate will use several configurations including cell-attached, whole cell and excised patch to record macroscopic currents and single channel activity. A demonstrated background in molecular biology and electrophysiology in mammalian cells or other systems (such as two-electrode oocyte voltage clamp) is strongly recommended.
The Lacroix laboratory and WesternU promote diversity and inclusion. The salary compensation for this position matches the NIH guidelines for post-doctoral stipends. WesternU offers competitive benefits and the Pomona area offers affordable housing and a comfortable climate 30 min away from downtown Los Angeles, the San Gabriel Mountains and the pacific coast and its sandy beaches.
To apply, please send a CV, a 1-2 page of research experience and career goals along with contact information for 3 references by email to: jlacroix at westernu.edu