Cell competition, a cell fitness sensing mechanism by which abnormal cells are eliminated during animal development, is receiving increasing attention because of its possible roles in the prevention and early development of cancer. The molecular mechanisms of cell competition and its physiological significance are still emerging. Cell competition may also be useful in regenerative medicine. For more details see Baker Curr Opin Cell Biology 48:40-46 2017; Maruyama & Fujita Curr Opin Cell Biology 48:106-112 2017.
Postdoctoral positions are available in the laboratories of Dr. Nicholas Baker and Cristina Montagna to study the mechanisms and physiological functions of cell competition using either Drosophila or mice, exploiting newly-derived mouse and Drosophila mutants. Elimination of unfit cells including aneuploid cells will be studied at the molecular level. Aneuploidy, the gain or loss of chromosomes, generates cells that contribute to birth defects, cancer and aging if not eliminated. Our research is interdisciplinary and involves molecular genetics, cell biology and biochemistry studies.
The successful applicant will have a PhD in a relevant discipline, ambitious scientific interests and the drive to succeed in scientific research. Experience in molecular biology or in Drosophila or mouse developmental genetics may be an advantage.
Albert Einstein College of Medicine is a premier, research-intensive medical school dedicated to innovative biomedical investigation and to the development of ethical and compassionate physicians and scientists. Postdoctoral fellows will be eligible for university housing and compensated according to NIH salary scales.
Applicants should send a cover letter and cv including publication list and contact information for 3 references as a pdf file to firstname.lastname@example.org
The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Einstein seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence, and the communities we serve.