Indiana University School of Medicine (IUSM)

Postdoctoral Positions in Stem Cell and Bioinformatics

Indiana University School of Medicine

Indianapolis, IN, United States

Postdoctoral Positions in Stem Cell and Bioinformatics

NIH funded post-doctoral associate positions are available in the Department of Pediatrics, Indiana University School of Medicine. The IU School of Medicine is the largest medical school in the United State and ranks top 33 NIH-funded medical schools in the nation. Compensation is at NIH scale. The successful candidate will have access to the generous retirement benefits package in Indiana University.

We study mechanisms of early human heart formation and human inherited cardiovascular diseases using human embryonic stem (ES) cell, patient-derived induced pluripotent stem (iPS) cell and mouse genetic models. Our lab has well-established platform for performing cellular and molecular studies with multiple publications (Developmental Cell. 2017. 42: 333-348; Nature Communications. 2013. 4; Nature. 2008, 453: 524-528). One position is for studying novel long non-coding RNAs in regulating early human heart development and heart disease. The successful candidate is expected to be self-motivated with a recent Ph.D. degree. The candidate is expected to have solid experience in molecular and cell biology, or mouse genetic models. Preference will be given to individuals with hands-on experience associated with RNA and/or epigenetic studies. Bioinformatics or mouse experimental skills are a plus.

The second position is for joint research labs of Dr. Lei Yang and Dr. Jun Wan at Department of Medical and Molecular Genetics. Dr. Jun Wan is director of Collaborative Core for Cancer Bioinformatics (C3B) shared by Indiana University Simon Cancer Center and Purdue University Center for Cancer Research. He has broad interests in using cutting edge technologies and approaches to study gene regulatory network, particularly to explore master regulators for gene programming and understand mechanisms of gene regulation. Their work have been published in high impact journals, e.g. Nature Nanotechnology, Cell, Molecular Cell, Journal of Clinical Investigation, PNAS, Nature Communications, eLife, Nucleic Acid Research. The successful candidate will have a unique multi-disciplinary collaboration opportunity to work with interdisciplinary teams of scientists including basic research and computational sciences. He/She is expected to use and/or develop novel computational approaches to analyze data of next generation sequencing (NGS) to support studies of early stage human heart development, disease and regeneration. A Ph.D. degree in Computer Science, Bioinformatics, Biostatistics, Biology, or a related field is required. The ideal candidate should have experience in NGS data analysis and be proficient in programming languages including R and Python.

Interested candidates should submit their CV including names and contact information of three references and a brief description of their research experience via e-mail to Dr. Lei Yang (lyang7@iu.edu) and Dr. Jun Wan (junwan@iu.edu).

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Postdoctoral Positions in Stem Cell and Bioinformatics