The Martin Lab at UC Berkeley is looking for a postdoc with strong expertise in biochemistry to address exciting questions about the mechanisms of protein quality control, ATP-dependent protein degradation, and the ubiquitin-proteasome system.
The successful candidate will work on a research program focusing on the 26S proteasome and related protein translocases of the AAA+ ATPase family, and investigate general ATPase motor function, ubiquitin-dependent substrate recognition/selection, and the principles of mechanical protein unfolding on the surface of ring-shaped ATPases.
In addition to a solid background in biochemistry, experience in structural biology, single-molecule manipulations, mass spectrometry, or cell biology would be beneficial, but is not required.
- Ph.D. in Biochemistry, Biophysics, or a related field, with a track record of publication in peer-reviewed journals.
Expertise In One Or More Of The Following Areas:
- In vitro biochemistry, enzyme kinetics
- Recombinant protein expression and purification
- Protein fluorescence and absorbance measurements
- Single-molecule TIRF microscopy or force measurements (tweezers, fleezers)
- Mass spectrometry
- Structural biology (X-ray crystallography or cryo-EM)
- Cell biology
- Demonstrated ability to work independently
- Excellent oral and written communication skills
To apply, please submit a single pdf that includes
- A cover letter describing your research and career goals, and your expertise in biochemistry or structure-function studies
- A curriculum vitae, including a list of publications with brief (2-3 sentence) descriptions of your contributions to the published work
- Contact information for 3-5 references
Please send your application to Andy Martin at email@example.com
HHMI is an equal opportunity employer.