University of Copenhagen (UCPH)

Postdoctoral position in Signaling processes in genome stability at the Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Copenhagen, Denmark

A fully funded postdoctoral position (for a duration of 2 years, with the possibility of extension for an additional 2 years) is available in the Mailand Group at Novo Nordisk Foundation Center for Protein Research (CPRwww.cpr.ku.dk), University of Copenhagen, Denmark.

Mailand Group at CPR
CPR promotes basic and applied discovery research on human proteins with medical relevance. The Center is a strong hub for cutting-edge research on protein signaling and human disease, comprising modern laboratories and state-of-the-art facilities within protein science.

Research in the Mailand Group aims to understand how signaling processes driven by ubiquitin, SUMO and other post-translational protein modifications (PTMs) orchestrate and regulate cellular responses to DNA damage and replication stress. We combine systems-wide proteomics- and functional genomics-based approaches with targeted methods within cell biology, biochemistry and advanced imaging to discover and functionally characterize cellular signaling responses that guard against genome instability and disease onset.

We offer a vibrant, ambitious and highly international research environment, as well as access to cutting-edge facilities within protein science, including state-of-the-art proteomics and microscopy platforms.

For more information, please visit: http://www.cpr.ku.dk/research/proteinsignaling/mailand/.

Job description and project
The successful candidate will join an ambitious international team investigating how cellular signaling processes protect against genome instability, a major driver of cancer and many other severe pathologies. Using proteomics- and CRISPR/Cas9-based screening approaches, we are now able to comprehensively map the proteins and PTMs that promote and regulate protective cellular responses to a variety of genotoxic insults.
The project aims to mechanistically dissect the functions of prospective novel human genome stability maintenance factors and signaling processes that we recently identified in such screens.

The selected candidate will also be involved in our ongoing efforts to develop innovative screening strategies for illuminating cellular signaling processes that operate in the context of genome maintenance responses. For these studies, the appointee will have the opportunity to apply a broad range of advanced cell-, biochemistry- and microscopy-based methodologies, as well as cutting-edge proteomics- and CRISPR-Cas9-based screening approaches.

Qualifications
We are looking for a highly motivated and ambitious candidate with:


  • A PhD degree in a relevant biological subject (genome stability maintenance, ubiquitin/SUMO, cell cycle, protein signaling, chromatin or related) and hands-on experience with methodologies in cell biology and/or biochemistry.

  • Documented publication record with at least one first author paper in an international peer-reviewed biological journal.

  • An open-minded, flexible and enthusiastic personality capable of interacting well within a group.

  • Excellent communication skills and sound command of English, both oral and written.

Terms of employment
The employment as Postdoc is a full time (37 hours per week) and fixed-term position for 2 years.

Projected starting date is Spring 2020 or later. Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at DKK 34,364 / EUR 4,581 (October 2019 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark for the last 10 years.

The position is described in the Ministerial Order on the Job Structure of Academic Staff at Universities of 11 December 2019.

Questions
For more information about the position, please contact Prof. Niels Mailand; e-mail: niels.mailand@cpr.ku.dk.

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application should be in English and must include the following documents in PDF format:


  1. Motivated letter of application.

  2. Curriculum Vitae.

  3. Diplomas (all relevant certificates collated into one file).

  4. List of publications.

  5. A maximum of 3 publications.


Application deadline: Sunday 9 February 2020 p.m., 23:59 CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not fulfil the abovementioned requirements.

Recruitment process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.


Apply Now


The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Please apply via recruiter’s website.

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