Italian Institute of Technology (IIT)

Postdoctoral Position in Parkinson’s Disease Research: multiscale neuronal circuit investigation - [ Postdoc ]

Italian Institute of Technology (IIT)

Genova, Italy

We are seeking highly motivated candidates to fill a postdoctoral position in the framework of the recently funded Horizon 2020 AND-PD (grant agreement n° 848002) research initiative, which involves an international consortium with partners working at the intersection between basic research and biomedical applications.

The project focuses on the investigation of the causative mechanisms involved in co-morbidities linking Parkinson’s Disease with Anxiety and Depression.

Parkinson’s Disease (PD) is clinically categorised as a movement disorder. However, approximately 40% of the PD patients experience comorbid anxiety and depression, which are complex mental conditions recognised as the leading cause of disability worldwide, and one of the strongest predictors of quality of life in PD. Their relationship and pathophysiology are, however, poorly understood.

To investigate the neuronal substrates of anxiety and depression in PD, the successful candidate will perform a programme of pre-clinical research using established disease animal models, multiscale neuronal circuit investigation and behavioral analysis.

We are looking for candidates with expertise in neurophysiological and optogenetics ex-vivo and/or in-vivo combined with viral-based approaches to deconstruct and manipulate neuronal circuits; together with confocal microscopy, this expertise is considered as a mandatory prerequisite. Previous experience with calcium imaging will be highly valued.

Within the Neuromodulation of Cortical and Subcortical Circuits research line of Istituto Italiano Di Technologia (Raffaella Tonini; https://www.iit.it/research/lines/neuromodulation-of-cortical-and-subcortical-circuits) the successful applicant will work in cutting-edge and highly collaborative research environment, and will also have the opportunity to train in the different laboratories of the research consortium to develop specific project tasks.

Candidates should hold a Ph.D. in either Physiology, Physics, Neuroscience, or related subjects, and have excellent written and verbal English communication skills. Applicants are expected to have a strong research track record and to be highly independent.

Salary will be commensurate to qualifications and experience and in line with international standards.

Applications, including detailed curriculum vitae, cover letter with an indication of the targeted laboratories, and name and contacts of 2 referees, should be submitted in PDF format to AND-PD@iit.it quoting “AND-PD Postdoctoral position CB 78055” in the subject line.

Please apply via recruiter’s website.

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