A Postdoctoral Scholar position is available immediately at University of California, San Francisco (UCSF) to study leukemia, with a primary focus on B-cell acute lymphoblastic leukemia (ALL). The Schjerven lab is located at the Parnassus campus of UCSF and is part of a large and active immunology and cancer research community. For more information on the research environment, see for example: https://immunox.ucsf.edu/ and http://cancer.ucsf.edu/ . Mentoring and collaboration are core values across the UCSF campus, providing an excellent environment for postdoctoral training. Our lab studies normal and malignant immune cell development and function, with a focus on the role of regulatory transcription factors. We use in vivo mouse models, flow cytometry, immunological methods, cell culture for functional assays, Cas9-mediated gene manipulations, genome-wide expression profiling (RNA-Seq) and chromatin analysis. Members in our lab work on projects ranging from immune cell development (hematopoiesis), leukemia and autoimmunity, and the main focus of this Post Doc position is to study molecular mechanisms of oncogenic growth in specific subtypes of Acute B-cell leukemia. We aim to increase our understanding of the molecular and biological consequences of specific mutations and discover vulnerabilities that can be targeted in precision medicine approaches. The project will require experience in Flow Cytometry, cell culture, gene manipulations (transductions) and general molecular biology. Additional examples of previous experience that would be beneficial (but not required) are experience with leukemia/cancer, mouse models, high throughput sequencing (‘omics’, e.g. RNA-Seq, etc), or background in general immunology.
The postdoctoral fellow will also be expected to contribute to other team-work efforts in lab, and will have opportunities for participation in external collaborations, as well as mentoring of student interns and junior lab members as part of career development.
We are seeking a highly motivated candidate with a Ph.D. degree in a relevant area of biology (e.g. molecular biology, cell biology, leukemia, cancer, immunology, hematology) who has a strong interest in academic research. Basic knowledge of cell and molecular biology is required, as well as previous experience with Flow Cytometry and gene manipulations in cell culture (transductions, etc). The candidate needs to be able to work independently and in a collaborative team, as well as being able to multitask, and present their research in both oral presentations and written reports.
- A Ph.D. in cell biology, molecular biology, or a relevant biological science.
- Strong communication skills in English, both written and spoken.
To apply, please send CV, including list of publications and names and contact info for 3 references, together with a letter of motivation to Hilde.Schjerven (at) ucsf.edu with the Subject ‘Post Doc in Leukemia’.
The advertisement is posted for 2 months (60 days) but to ensure consideration, interested candidates should submit their application before June 26th. Thereafter, applicants will be evaluated on a rolling basis, until position is filled.