Postdoctoral researcher position available to study signaling pathways in the immune system
The Department of Physiology at UCLA is seeking to recruit a highly motivated postdoctoral fellow immediately with extensive training in molecular biology and immunology, including experience in working with small animals. Our laboratory has made important contributions to the field of store-operated Ca2+ (SOC) entry in immune cells, including identification of the components of the SOC channels, characterization of their biochemical and functional properties using biochemical (protein purification), biophysical (whole cell patch-clamp recordings), imaging (confocal and TIRF) and genetic (knockout animals) tools. Our recent research identified novel function of a SOC channel component in cellular nucleic acid sensing pathway. Our research utilizes cellular and organismal studies using primary human and murine immune cells and knockout mice.
The ideal candidate will be a recent Ph.D. graduate, with a strong background in life science research exemplified in two first author publications. The trainee will learn cutting edge molecular biology, cell biology and high-resolution imaging techniques, including high throughput screens, genome editing, single-cell calcium imaging, analysis of knock out cells/mice, as well as in vivo experiments with animal models of multiple sclerosis or pathogen infections. Applicants should possess strong bench, collaboration and communication skills.
Please refer to our publications for further information (Nature 2006, Nature Cell Biology 2010, PNAS 2012 and 2016, Science Signaling 2016, Nature Immunology 2019). Interested applicants should send a cover letter explaining relevant work experience (less than 1 page), curriculum vitae and contact details of three referees by e-mail. Please visit our webpage for a brief overview of our work. https://www.physiology.ucla.edu/faculty/srikanth.html
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see (http://policy.ucop.edu/doc/4000376/NondiscrimAffirmAct).