Institute of Organic Chemistry and Biochemistry, ASCR

Post-doctoral position in Cryo-EM

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Prague, Czech Republic

A fellowship-funded postdoc position is open in Dr Sebastian Zoll’s group at IOCB Prague. Dr Zoll’s group is using a combination of biochemical, biophysical, immunological and structural biology techniques to understand the mechanisms of host-pathogen interactions. The successful candidate will use Cryo-EM to determine the structure of a viral capsid protein in complex with its cellular receptor. As part of this process, the applicant will generate monoclonal antibody and nanobody libraries as tools as well as for therapeutic applications.


PhD in structural biology using Cryo-EM as the main tool. Expertise in grid preparation, microscope operation and data processing in RELION is essential. Knowledge in X-ray crystallography and SAXS is a bonus but not necessary.
Experience in expression construct design, protein purification and biophysical techniques to analyze protein-protein interactions (ITC or SPR).

Additional information

Duration – The fellowship is granted for one year with possible extension by one more year.

Start – The earliest starting date is May 2020.

More information –

Please send a short motivation statement (max. 500 words) and a copy of your CV to

Feel free to contact Sebastian for informal inquiries.

Apply with CV and Cover Letter

Must be a .doc, .docx, or .pdf file and no larger than 1MBMust be a .doc, .docx, or .pdf file and no larger than 1MB

Post-doctoral position in Cryo-EM