A POSTDOCTORAL position is available in Toronto/Canada, in the laboratory of Dr. Hakem at the Princess Margaret Cancer Centre/University Health Network;one of the top five cancerresearch centres in the world.
Our research program focuses on i) better understanding the mechanisms that drive cancer development and ii) identification of novel cancer therapeutic strategies.
The lab has excellent track records studying tumor suppressors (e.g. BRCA1 and TP53), in vivocancer mechanisms and signaling pathways (e.g. Notch pathway). Our studies have been published in journals that include Nature Immunology (1,77-82), Genes & Dev(18:1144-1153), Science(304:1822-1826), JEM(207: 983-97),J Clin Invest(128: 4525-4542), and Nature Communications(DOI: 10.1038/ncomms12638).
Genetics, proteomics, transcriptomics, bioinformatics, Genome-wide CRISPR-Cas9 screening, biochemistry and molecular analyses of human cancer cells, mouse models and PDXs, as well as data from cancer patients are used for our studies.
- PhD or MD/PhD degree obtained within the past 3 years
- Demonstrated expertise in biochemistry, molecular biology and Genome-wide CRISPR-Cas9 screening
- Highly self-motivated and creative individual with high quality first author publications
- Expertise in bioinformatics analysis is a plus
- Excellent writing and communication skills
- Ability to work effectively both independently and as a member of a team is a prerequisite.
Interested applicants should submit their CV, names of three referees and a statement of research interest to Dr. Hakem (email@example.com).