Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac)
Postdoctoral position: Genomic determinants of Enterovirus D68 neurotropism
University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Project Title: Genomic determinants of Enterovirus D68 neurotropism
Institution: VIDO-InterVac, University of Saskatchewan
120 Veterinary Road, Saskatoon, SK S7N 5E3
Start Date: The position is available immediately
Organization: VIDO-InterVac is a preeminent research institute focused on infectious disease research and vaccine development. VIDO-InterVac currently has over 150 personnel and state-of-the-art facilities that include the International Vaccine Centre (InterVac) – one of the largest and most advanced containment level 3 facilities in the world.
Project Description: Recent studies in human neuronal cells and our research in microglia demonstrated different tropism of historical and contemporary EV-D68 strains. The goal of the project is to understand EV-D68 genomic determinants of this distinct tropism. The candidate will use reverse genetics systems and wild-type contemporary and historical strains to generate EV-D68 chimeras. Viral replication and infectivity will be assessed in neuronal cells, neuronal progenitor cells, and microglia. Pathogenesis in mice will be also addressed.
Financial Support: The project is fully funded for two years.
Research Advisor: Uladzimir Karniychuk, DVM, Ph.D. For more information, visit:
Candidate Profile: Candidates must hold a PhD in virology, molecular biology, or another appropriate discipline. Recent PhD graduates are particularly encouraged to apply. Well-developed oral and written communication skills are essential. An ideal candidate will have a strong background in classical and molecular virology techniques, immunohistochemistry, flow cytometry, and western blot. Experience working with animals is not essential.
The candidate must be highly motivated, creative, and diligent. The successful candidate will be required to undergo and clear a reliability status screening assessment, background check and a criminal record check as a condition of employment.
How to Apply:
Interested candidates must submit (pdf files) 1) a letter of motivation, 2) a complete curriculum vitae (CV) and contact information for individuals willing to provide a reference for the candidate, online at: http://vido-intervac.humi.ca/job-board/uncategorized/1252
VIDO-InterVac and the University of Saskatchewan is strongly committed to a diverse and inclusive workplace. As such, applications from those who will contribute to the diversity of our community are welcome and all qualified candidates are encouraged to apply. However, Canadian citizens and permanent residents will be given priority.
Only candidates selected for interviews will be contacted.