The University of Arkansas for Medical Sciences, Division of Hematology/Oncology, is searching for two post-doctoral researchers in the laboratory of Michael Birrer, M.D., Ph.D., Director of the Winthrop P. Rockefeller Cancer Institute. The laboratory focus is on the genomics of ovarian cancer and how it can be translated into better management of patients suffering from the disease. The laboratory will be the center piece of a new program in women’s cancers.
Extramurally funded projects for this position include: biomarker identification for the early detection of ovarian cancer (U01CA152990), identification of “driver” genes in advanced stage ovarian cancer, proteomic analysis of platinum resistant ovarian cancer (DOD W81XWH-17-1-0225), creation of 3D and mouse models of ovarian cancer (R21CA218973), testing of novel therapeutic agents against the disease (U01CA214114), and characterizing the molecular features of long-term survivors (DOD W81XWH-16-2-0038).
Accepted candidates will be exposed to state of the art genomic and cancer biologic investigations including whole transcriptome signatures, methylation patterns and copy number variation. In addition, post-doctoral fellows will characterize the biologic impact of genomic alterations on cell migration, invasion and metastasis in vitro along with testing their effects in vivo in validated animal models. Finally, given the translational nature of the laboratory, fellows will have the opportunity to participate on projects which utilize human tissues, patients on clinical trial, and new drugs from the biotech field.
A Doctoral Degree in cancer/cell/molecular biology, proteomics, computational biology, biochemistry or related field required. Expertise in tissue culture, protein biochemistry & molecular biology technique, immunofluorescence microscopy, RNAseq, analysis of large datasets, animal work preferred. This position requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical including a drug screen.
Successful applicants will join one of the most prestigious cancer centers in the country. The Winthrop P. Rockefeller Cancer Institute has been one of the nation’s premier cancer centers for more than three decades, and it is the only cancer center in the state of Arkansas with a robust cancer research portfolio and a mission to improve cancer outcomes for all Arkansans. The Cancer Institute treats over 2,500 new cancer patients annually and has an extensive effort focused on delivering cancer care and conducting research in underserved populations. Its 135 members conduct outstanding cancer research in multiple scientific programs. Cancer Institute members receive approximately $10 million in extramural cancer research funds annually, including multiple “team science” grants. The Cancer Institute has 5 institutional shared resource facilities. A robust clinical trial infrastructure currently supports nearly 270 cancer clinical trials. The University of Arkansas for Medical Sciences is one of 57 institutions with an NIH Clinical and Translational Science Award, which supports translational research and creates a supportive environment that synergizes with the Winthrop P. Rockefeller to promote junior investigators and transdisciplinary research.”
The Winthrop P. Rockefeller Cancer Institute offers a competitive salary, outstanding benefits, participation in workshops and conferences, high quality shared resources, and many opportunities for continued professional development.
Applicants should submit their current curriculum vitae firstname.lastname@example.org with the subject line reading, “Post-Doctoral application.”
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