Postdoctoral Fellow – Kapahi and Campisi labs
Postdoctoral position to study the impact of advanced glycation endproducts (AGEs) in aging and Alzheimer’s disease in iPSCs and mouse models.
This is a joint position between the Kapahi and Campisi Laboratories at the Buck Institute for Research on Aging. The Kapahi and Campisi laboratories are collaborating to study the role of advanced glycation endproducts (AGEs) in gliosis and cellular senescence and its relevance to human metabolic diseases and aging. This is being achieved by using an interdisciplinary approach combining genetic, pharmacological, biochemical, and genomic approaches in invertebrate model systems, mice, and human samples. The broader significance of this research is to help uncover the role of diet and AGEs in the etiology of age-related human diseases like diabetes and Alzheimer’s disease. The current position involves studying the role of glucose and Advanced Glycation Endproducts (AGEs) in diabetes and neurodegeneration using invertebrate models, mice and IPS derived cells. We propose to examine the mechanisms involved in synthesis and detoxification of Advanced Glycation Endproducts (AGEs) and how they cause cellular damage.
- Previous background in mouse genetics required
- Willingness to write grants and manuscripts essential
- Candidate will receive training in to progress towards an independent career.
Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. We are an independent, non-profit institution located in Marin County, CA, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging—the number one risk factor for diseases including Alzheimer’s, Parkinson’s, cancer, macular degeneration, heart disease, and diabetes—the Buck seeks to help people live better longer.
The Buck Institute has an exceptional postdoctoral research program. We offer competitive salaries, excellent benefits, a dynamic work environment, and new state-of-the-art facilities.
LIVING BETTER LONGER TOGETHER
Buck Institute for Research on Aging is an equal opportunity employer. Buck Institute seeks candidates whose experience and qualifications will enable them to contribute to our dedication to diversity and excellence. We are committed to building an organization that represents a variety of backgrounds, perspectives and skills. We welcome the unique contributions that you can bring in terms of education, opinions, culture, ethnicity, race, sex, gender identity and expression, nation of origin, age, languages spoken, veteran’s status, color, religion, disability, sexual orientation and beliefs.
Interested candidates should apply online and upload a CV and cover letter including contact information for three professional references. For questions regarding this position, please email Pkapahi@buckinstitute.org or visit https://www.buckinstitute.org/lab/kapahi-lab/