Helmholtz Association of German Research Centres

Postdoctoral Fellow in crosstalk between Epigenetics, Metabolism and Vascular Biology in Leipzig (f/m/d)

Helmholtz Zentrum München, German Research Center for Environmental Health

Munich, Germany

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases. To achieve this, it investigates the interaction of genetics, environmental factors and lifestyle.

The newly founded Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) at the University of Leipzig is part of the Helmholtz Zentrum München and aims to uncover the molecular underpinnings of metabolic, obesity and vascular disorders to enable precision therapies. As one of the world’s leading research institutes, the Helmholtz Zentrum München is a highly driven and stimulating international environment. Together with renowned scientists and supported by state-of-the-art infrastructure, you will have the opportunity to make important contributions towards scientific knowledge and the improvement of people’s quality of life at our institue in Leipzig.

The Vascular Epigenetics group at the Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) is now recruiting a

h.1 Postdoctoral Fellow in crosstalk between Epigenetics, Metabolism and Vascular Biology in Leipzig (f/m/d)

Job Description

The ascular Epigenetics group, headed by Dr. Bilal Sheikh, elucidates the molecular mechanisms that underpin the complex interplay between metabolic, lifestyle and epigenetic factors. The group focuses on these themes in the context of vascular function and vascular disease. In close partnership with the Medical Faculty of the University of Leipzig and the University Hospital Leipzig, we aim to translate our discoveries into effective therapies against vascular dysfunction in a variety of pathologies.

The successful applicant will have the opportunity to work on one or more exciting projects that span the fields of epigenetics, metabolism and vascular biology. The projects will involve dissecting molecular mechanisms and phenotypic changes in animal models using state-of-the-art techniques such as single cell technologies (10x genomics), next-generation sequencing, chromatin analyses and mass spectrometry based metabolomics. In addition, human clinical samples will be available for translational research.

Your Qualifications

The ideal applicant should be highly motivated, have good communication skills and be able to independently drive research projects. A background in mammalian cell culture techniques and animal models is required. Experience with Crispr/Cas9 technology, flow cytometry, bioinformatic analyses (in R) and single-cell technologies would be beneficial. The candidate should have completed (or shortly will complete) a highly successful PhD with at least one first author paper in a reputable international journal.

Our Offer

The HI-MAG offers a world-class, international and highly collaborative environment with extensive scientific resources. We provide you with a challenging and versatile workplace, allowing you the freedom to follow your instincts and be creative. With state-of-the-art infrastructure and personalized career-support, we prioritize your development and help you achieve your career goals.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (TV EntgO Bund). The activity involves special knowledge and experience specific to own scientific skills.

The position is available from 01.02.2020 and is initially offered for two years with a possible extension.

As a holder of the Total E-Quality Award, we promote equality of opportunity. To increase the share of women in management positions we very much welcome the respective applications. Qualified applicants with physical disabilities will be given preference.

Curious? For administrative questions please contact Dr. Konstanze Julich-Gruner on +49 341 9715373, for scientific questions please contact Dr. Bilal Sheikh (bilal.sheikh@helmholtz-muenchen.de)

We are looking forward to receiving your comprehensive online application until November 20th, 2019 including a motivation letter covering research interests, CV, list of publications and at least two reference letters along with the contact details of referees.

Please apply via recruiter’s website.

Quote Reference: 2019/0344