Department of Oncology / McArdle Laboratory for Cancer Research, UW-Madison

Postdoctoral Fellow

McArdle Laboratory of Cancer Research, University of Wisconsin-Madison

Madison, WI, United States

Postdoctoral Fellow
Laboratory of Dr. Yongna Xing

McArdle Laboratory of Cancer Research
Wisconsin Institutes for Medical Research (WIMR) II 6451
University of Wisconsin-Madison
1111 Highland Ave
Madison, WI 53705

Two postdoctoral positions, one on structural biology and one on cell biology, are available to investigate the mechanisms and cellular functions of phosphatase signaling complexes and their disease mutations in cancer and intellectual disability. We combine cryo-EM, x-ray crystallography, cell biology, system biology, biochemistry, computational biology, and bioinformatics to gain critical knowledge on complex phosphatase signaling network dictated by both allosteric structured cores and versatile signaling motifs. The research is performed in a highly multidisciplinary setting with basic scientists with expertise on Cryo-EM, biochemistry, cell biology, bioinformatics and chemical biology. We are well equipped for multidisciplinary research, such as powerful GPU computer, liquid handling crystallization robot, and live cell imaging system. In addition, our lab is conveniently located near multiple shared facilities. Our research is built on collaborations with more than 10 groups from US and Europe as well as dynamic collaborations on campus in both basic and clinical research. UW-Madison has highly collaborative research environment that easily establish novel collaborations.

We are seeking productive, and motivated individuals with excellent organizational, interpersonal, and communication skills (both verbal and written). We expect our structural biologists have strong expertise in either cryo-EM or x-ray crystallography, protein biochemistry, system biology and application of in-house bioinformatic tools. Our cell biologists have strong expertise in cell biology, cancer research, system biology, molecular biology, and application of bioinformatic tools. We expect our candidates feel comfortable to work both independently and by collaboration toward personalized medicine for phosphatase diseases.

The starting salary for promising candidate will be $48,000 or above.

Review of applications will begin immediately and continue until the position is filled. To apply: Please send a cover letter, CV and the names and contact information for three references to Dr. Yongna Xing via email:

Under-represented minorities are encouraged to apply.


Apply with CV and Cover Letter

Must be a .doc, .docx, or .pdf file and no larger than 1MBMust be a .doc, .docx, or .pdf file and no larger than 1MB

Postdoctoral Fellow