Wellcome Trust Sanger Institute

Postdoctoral fellow - Computational Biology

Wellcome Sanger Institute

Cambridge, United Kingdom

The Opportunity:
We are looking for a highly motivated post-doctoral fellow in bioinformatics to contribute to the analysis of single cell genomics data. The role will be based in Dr. Sarah Teichmann’s laboratory at the Wellcome Sanger Institute, supervised by Dr Kerstin Meyer. The primary role of the post is the analysis of single cell data generated by the human cell atlas projects, in particular relating to lung biology over the life span, and lung diseases including infection. Depending on expertise and interest there will be opportunities to contribute to the development of the analysis pipelines in conjunction with the Cellular Genetics core bioinformatics team and/or establishing the pipelines that will facilitate visualisation of the Human Cell Atlas (HCA) data via dedicated data portals.

About HCA:
The HCA project aims to build comprehensive reference maps of all human cells. These maps will provide a basis for both understanding human health and the molecular basis of disease. For more information about the HCA project click here. The human cell atlas will be transformational in our understanding of lung biology and will facilitate the description of the molecular and cellular changes associated with lung disease. The post will be available for two years in the first instance.

About the Role:
Your role will include the following tasks:
• Using single cell analysis packages to analyse and interpret single cell gene expression and other single cell -omics data
• To implement and develop tools to analyse spatial gene expression data
• Keeping up to date with new experimental and analytical developments in the field of single cell genomics
• Understanding the cellular landscape of the lung in health and disease
• Collaborating with experimental teams at the Wellcome Sanger Institute working on single cell transcriptomics
• Writing high impact scientific papers for publications in the scientific literature
• Providing bioinformatics expertise for a range of research projects within the Teichmann lab
• Representing the team and the institute at HCA project meetings and international scientific conferences.

About You:
You will be an excellent communicator with competent knowledge of programming languages such as Python, Perl and R. You will be a team player with the ability to manage your own workload whilst also maintaining flexibility to adapt due to the nature of working in scientific environments. You will have the opportunity to make important contributions to the full range of research our group is engaged in.

Essential Skills
• Degree in computer science, bioinformatics or a scientific discipline
• Competency in programming languages e.g., Python, Perl, R
• Ability to learn new programming languages as required
• Familiarity with developing in a UNIX/Linux environment
• Experience using and developing databases, e.g., Oracle, MySql
• Experience in web development
• Interest in bioinformatics and molecular biology
• Ability to work with others in a collegiate and collaborative manner
• Ability to work independently, prioritise workload and efficiently meet deadlines
• Proven ability to develop and maintain effective working relationships with wide range of persons of differing levels, abilities and knowledge
• Ability to effectively communicate ideas and results to collaborators and present orally groups
• Demonstrates inclusivity and respect for all

Ideal Skills
• MSc in Computer Science, Bioinformatics or related field
• Experience of molecular biology/other biological fields
• Experience of statistical analyses
• Experience of analysing complex data sets
• Experience of developing analytical pipelines
• Experience of running code in high performance computing environments

Other information
Please include a cover letter and CV with your application.
Closing Date: 8th March 2020

About Us
The Wellcome Sanger Institute is a world leading genomics research centre. We undertake large-scale research that forms the foundations of knowledge in biology and medicine. Our findings are used to improve health and to understand life on Earth. Find out more at www.sanger.ac.uk or follow us on Twitter, Facebook, LinkedIn, Youtube and on our Blog.

Our campus
Set across 130 acres, just outside of Cambridge, The Sanger Institute is located on the stunning Wellcome Genome Campus. Home to some of the world’s foremost institutes and organisations in genomics and computational biology, committed to delivering life-changing science with the reach, scale, and creativity to solve some of humanity’s greatest challenges.

Our benefits:
There’s an attractive benefits package on offer at the Genome Wellcome Campus. We appreciate the importance of achieving work-life balance and support this with a number of family and carer-friendly policies. Plus a flexible working policy for those who may wish to amend their working pattern or arrangement.
As well as the usual benefits you would expect, we go much further:
• 25 days annual leave (extra 1 day to a maximum of 30 days for every year you work)
• Auto-enrolment into a generous Group Defined Contribution Pension Scheme, with enhanced company contribution (for more information, see our Pensions page)
• Up to 2 days annual paid volunteering leave
• Up to 10 days paid Emergency Carers Leave per year
• Family friendly environment including options for flexible and part-time working, an on-site Workplace Nursery salary Sacrifice Schemes for pre-school children and Summer holiday club
• Life Assurance Cover and a Group Income Protection Scheme (if on a contract of 12 months or more)
• Enhanced maternity leave and parental leave
• Access to substantial number of courses and training events onsite
• Private Healthcare Scheme (after 6 months service)
• Eyecare and Dental payment plans
• Concessions and discounts from our corporate perks site

Being part of the Genome Wellcome Campus you will be part of the beautiful working environment with an impressive range of benefits, services and facilities also including:
• Free bus service to and from Campus, covering various routes around Cambridge, Saffron Walden and surrounding villages
• A car-share initiative
• Free parking
• A number of on-site venues where you can meet, eat and socialise with colleagues
• A thriving Sports and Social Club which provides members with subsidised access to a gym, tennis courts, sports hall, fitness classes and a vibrant social calendar of events

Find out more about our Genome Wellcome Campus.

We hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.

Please apply via recruiter’s website.