Weill Cornell Medicine (WCM), Cornell University

Post-Doctoral Fellow - Cancer Immunology

Weill Cornell Medicine

New York, NY, United States

Principle Investigator: Prof. Xiaojing Ma (email: xim2002@med.cornell.edu)

Job description: Seeking a post-doctoral research associate in the Department of Microbiology and Immunology. The laboratory projects will involve preclinical modeling that involves a novel E3 ubiquitin ligase (UBR5) and its immunoregulatory activities in tumor cells as well as the associated tumor microenvironment. The primary tumor model systems used will include orthotopic syngeneic and genetically engineered models of breast and ovarian cancers.

References: a. E3 ubiquitin protein ligase UBR5 drives the growth and metastasis of triple negative breast cancer. Cancer Res. Apr 15;77(8):2090-2101, 2017. PMID: 28330927 b. Targeting Ubiquitin Protein Ligase E3 Component N-Recognin 5 in Cancer Cells Induces a CD8+ T Cell Mediated Immune Response. Oncoimmunology. Apr 14;9(1):1746148, 2020. PMID:32363114 c. Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages. Nat Commun. Dec 8;11(1):6298, 2020. PMID: 33293516

Application: To apply, please contact: Prof. Xiaojing Ma (email: xim2002@med.cornell.edu)

Diversity is one of Weill Cornell Medicine’s core values and is essential to achieving excellence in patient care, research, and education. We welcome applications from candidates who share our commitment to fostering a culture of fairness, equity, and belonging. Weill Cornell Medicine is an Equal Employment Opportunity Employer, providing equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.Weill Cornell Medical College is an employer and educator recognized for valuing AA/EEO, Protected Veterans, and Individuals with Disabilities.

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Post-Doctoral Fellow - Cancer Immunology