The Department of Cellular and Integrative Physiology in the Long School of Medicine at the University of Texas Health San Antonio is seeking highly motivated postdoctoral fellows to engage in NIH-funded ongoing studies related to endocannabinoid signaling in synaptic plasticity and learning and memory as well as in neurodegenerative diseases in Dr. Chen’s laboratory. Specifically, the current research projects in his laboratory are focusing on defining the mechanisms of neurodegenerative diseases, including Alzheimer’s disease (AD) and traumatic brain injury (TBI)-induced AD-like disease, and identifying novel therapeutic targets for these neurodegenerative diseases. Dr. Chen’s laboratory employs a variety of approaches, including molecular biology, epigenetics, electrophysiological recordings, fluorescent and laser imaging, LC-MS-MS mass spectrometry, and behavioral tests, to elucidate cellular, molecular, and epigenetic mechanisms underlying pathogenesis and neuropathology of AD and TBI-induced AD-like neuropathology. We have a highly interactive and dynamic research environment, and encourage collaborations with colleagues across disciplines. Applicants should have a PhD and/or MD in neuroscience or related fields. We are seeking applicants with experience in epigenetics, bioinformatics, molecular cloning, and in vivo Ca2+ imaging and optogenetics. We are particularly interested in applicants with research experience in studying neuron-glia and/or astrocyte-microglia interactions.