NIH National Institute on Aging (NIA)

Postdoctoral - Computational and Molecular Biology

NIH National Institute on Aging (NIA)

Baltimore, MD, United States

The Laboratory of Genetics and Genomics at the National Institute on Aging (NIA) and the National Institutes of Health (NIH) is recruiting for postdoctoral positions in the newly established lab of Dr. Emmanouil (Manolis) Maragkakis. Dr. Maragkakis’ lab is interested to discover the mechanistic basis for RNA regulation and mRNA decay in health and disease and to bridge the gap between genetics and therapeutics. Projects in the lab follow data-driven approaches, are highly integrative and employ wet and computational approaches to extract mechanistic insight for biological processes. Of particular biological interest to the lab is the crosstalk and interplay between regulatory processes such as miRNAs or RNA binding processes with mRNA decay.

 

There are two positions available, one for computational biology and one for molecular biology.

o  The computational biology and bioinformatics position focuses on developing and applying advanced computational tools for large-scale data integration and analysis of sequencing data from novel technologies such as nanopore sequencing. Selected individuals will have great opportunities to train on wet-biology and candidates interested in this direction are encouraged to apply. Candidates must be strongly motivated, have or be very close to obtaining a PhD in bioinformatics, computational biology or related discipline and have no more than one year of postdoctoral experience. Candidates with an interest in machine learning, genomics, genetics and systems biology are particularly encouraged to apply. Successful applicants should have a strong background in programming (e.g. Python, R, Go) and a strong research background evidenced by at least one first-author publication. Prior experience with RNA biology will be considered a plus. Applicants must possess good communication skills and be fluent in both spoken and written English.

o  The molecular biology positions focuses on developing new protocols and analyses to study gene expression, translation and decay using nanopore sequencing. Anticipated methodologies include development of transcriptome-wide approaches including ribosome profiling (Ribo-Seq) and crosslinking and immunoprecipitation of RNA binding proteins coupled with sequencing (CLIP-Seq). Selected individuals will have great opportunities to train on computational biology and candidates interested in this direction are especially encouraged to apply. Candidates must be strongly motivated, have or be very close to obtaining a PhD in biological sciences and have no more than one year of postdoctoral experience. Candidates with an interest in mRNA degradation, miRNAs and RNA binding proteins are particularly encouraged to apply. Successful applicants should have a strong background in molecular biology, cell biology, biochemistry and a strong research background evidenced by at least one first-author publication. Prior experience with computational methodologies will be considered a plus. Applicants must possess good communication skills and be fluent in both spoken and written English.

 

To Apply:

Interested candidates should reference “EMRecruit” in the subject line and submit their curriculum vitae, a concise statement of their research interests, and the names and contact information for three references by email to Tina Roberson at robersonti@mail.nih.gov.

 

DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs.


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Postdoctoral - Computational and Molecular Biology